Results 21 to 30 of about 9,294,284 (160)

Design and Identification of a Novel Antiviral Affinity Peptide against Fowl Adenovirus Serotype 4 (FAdV-4) by Targeting Fiber2 Protein [PDF]

Viruses, 2023
Outbreaks of hydropericardium hepatitis syndrome caused by fowl adenovirus serotype 4 (FAdV-4) with a novel genotype have been reported in China since 2015, with significant economic losses to the poultry industry. Fiber2 is one of the important structural proteins on FAdV-4 virions.
Xiao Chen, Qiang Wei, Fusheng Si, Fangyu Wang, Qingxia Lu, Zhenhua Guo, Yongxiao Chai, Rongfang Zhu, Guangxu Xing, Qianyue Jin, Gaiping Zhang   +10 more
core   +5 more sources

Domain in Fiber-2 interacted with KPNA3/4 significantly affects the replication and pathogenicity of the highly pathogenic FAdV-4 [PDF]

Virulence, 2021
The outbreaks of hepatitis-hydropericardium syndrome (HPS) caused by the highly pathogenic serotype 4 fowl adenovirus (FAdV-4) have caused a huge economic loss to the poultry industry globally since 2013. Although the Fiber-2 has been identified as a key virulent related factor for FAdV-4, little is known about its molecular basis.
Quan Xie, Luyuan Li, Tuofan Li
exaly   +5 more sources

Rapid detection of FAdV-4 by one-tube RPA-CRISPR/Cas12a assay [PDF]

Frontiers in Microbiology
IntroductionFowl adenovirus serotype 4 (FAdV-4) is a highly contagious viral pathogen of global significance that affects various avian species. It primarily infects poultry and wild birds, leading to avian inclusion body hepatitis (IBH) and hepatitis-hydropericardium syndrome (HHS).
Lei Ma, Xueping Wang, Mingliang Zhang, Mengjie Zhu   +3 more
core   +5 more sources

Serological and Pathogenic Analyses of Fowl Adenovirus Serotype 4 (FAdV-4) Strain in Muscovy Ducks [PDF]

Frontiers in Microbiology, 2018
Hydropericardium hepatitis syndrome (HHS) is a lethal disease caused by Fowl adenovirus serotype 4(FAdV-4) that mainly infects 3- to 6-week-old broiler chicks. In 2015, an infectious disease characterized similar symptom to HHS in broilers outbroke in commercial duck flocks in Shandong province.
Xianglong Yu, Xianglong Yu, Xianglong Yu, Zhenzhong Wang, Zhenzhong Wang, Zhenzhong Wang, Hao Chen, Hao Chen, Hao Chen, Xiaoyu Niu, Xiaoyu Niu, Xiaoyu Niu, Yanguo Dou, Yanguo Dou, Yanguo Dou, Jing Yang, Jing Yang, Jing Yang, Yi Tang, Yi Tang, Yi Tang, Youxiang Diao, Youxiang Diao, Youxiang Diao   +23 more
core   +5 more sources

Acclimation of suspension LMH cell line for high-efficient inactivated FAdV-4 vaccine production [PDF]

Poultry Science
Fowl adenovirus serotype 4 (FAdV-4) is the main pathogen of hepatitis-hydropericardium syndrome (HHS) and mainly prevented and controlled through inactivated vaccine vaccination. In this study, to improve manufacturing efficiency and quality of inactivated virus vaccine, adherent Leghorn Male Hepatoma cell line (LMH-TB) was adapted to suspension growth
Heng Zhang, Min Liao, Xiangxiang Gao, Xijuan Xue, Hongwei Cao   +4 more
core   +5 more sources

Development of a Multiplex Conventional PCR Assay for Concurrent Detection of FAdV-4, FAdV-8b, and FAdV-11 [PDF]

Veterinary Sciences
Fowl adenovirus (FAdV) belongs to the Aviadenovirus genus within the Adenoviridae family. FAdVs are widely distributed and associated with various diseases in poultry, including adenoviral gizzard erosion (AGE), hepatitis-hydropericardium syndrome (HHS), and inclusion body hepatitis (IBH).
Su-kyung Kang, Dam-Hee Park, Kyeongcheol Min, Sung-Sik Yoo, In-Joong Yoon, Jongseo Mo   +5 more
core   +5 more sources

Evaluation of the Immune Effect of a Trivalent Fowl Adenovirus Inactivated Vaccine Against FAdV-4/8a/8b [PDF]

Veterinary Sciences
Fowl adenovirus can cause various diseases such as hepatitis-hydropericardium syndrome (HHS) and inclusion body hepatitis (IBH), which leads to huge economic losses for China’s poultry industry. In recent years, the prevalence of FAdV-4, FAdV-8a, and FAdV-8b has been on the rise.
Yulan Jiao, Qianhui Zhao, Yulong Zhao, Yingjie Li, Sumin Pan, Yinming Li, Yuntao Liu, Wanyu Shi   +7 more
core   +5 more sources

Requirement of Cellular Protein CCT7 for the Replication of Fowl Adenovirus Serotype 4 (FAdV-4) in Leghorn Male Hepatocellular Cells Via Interaction with the Viral Hexon Protein

Viruses, 2019
Fowl adenovirus serotype 4 (FAdV-4) causes hepatitis-hydropericardium syndrome (HHS), leading to severe economic losses in the poultry industry. Although the pathogenesis of FAdV-4 infection has caused much attention, the underlying molecular mechanisms ...
Junfeng Gao, Yongqiang Wang, Shijun J Zheng   +2 more
exaly   +4 more sources

An optimized sandwich ELISA for quantitative detection of fowl adenovirus serotype 4 (FAdV-4) in chickens [PDF]

Poultry Science
Fowl adenovirus serotype 4 (FAdV-4) causes hydropericardium-hepatitis syndrome (HHS) in chickens, resulting in severe economic losses worldwide. Fast and accurate diagnostic methods for FAdV-4 are required to monitor its prevalence and provide plausible ...
Huimin Ma, Yuhang Zhou, Shipeng Wang, Xiangyu Xie, Ruiji Chen, Qi Zheng, Lisha Zha, Xinyue Chang   +7 more
doaj   +4 more sources

Precise location of three novel linear epitopes using the generated monoclonal antibodies against the Knob domain of FAdV-4 surface structural protein, fiber1 [PDF]

Frontiers in Cellular and Infection Microbiology
BackgroundFowl adenovirus serotype 4 (FAdV-4) is the main pathogen of hepatitis-hydropericardium syndrome (HHS), which brings huge economic losses to the poultry industry worldwide. Fiber-1 protein plays an important role in viral infection and pathogenesis by binding directly to cellular receptors of FAdV-4.
Yongxiao Chai, Yongxiao Chai, Qianyue Jin, Rongfang Zhu, Zhenhua Guo, Qingxia Lu, Shujun Chai, Yunrui Xing, Lu Han, Guangxu Xing, Gaiping Zhang, Gaiping Zhang, Gaiping Zhang   +12 more
core   +5 more sources