Results 21 to 30 of about 12,747,404 (156)

Domain in Fiber-2 interacted with KPNA3/4 significantly affects the replication and pathogenicity of the highly pathogenic FAdV-4 [PDF]

Virulence, 2021
The outbreaks of hepatitis-hydropericardium syndrome (HPS) caused by the highly pathogenic serotype 4 fowl adenovirus (FAdV-4) have caused a huge economic loss to the poultry industry globally since 2013. Although the Fiber-2 has been identified as a key virulent related factor for FAdV-4, little is known about its molecular basis.
Aijian Qin, Wei Gao, Tuofan Li
exaly   +6 more sources

Evaluation of the Immune Effect of a Trivalent Fowl Adenovirus Inactivated Vaccine Against FAdV-4/8a/8b. [PDF]

Vet Sci
Fowl adenovirus can cause various diseases such as hepatitis-hydropericardium syndrome (HHS) and inclusion body hepatitis (IBH), which leads to huge economic losses for China’s poultry industry. In recent years, the prevalence of FAdV-4, FAdV-8a, and FAdV-8b has been on the rise.
Jiao Y, Zhao Q, Zhao Y, Li Y, Pan S, Li Y, Liu Y, Shi W.   +7 more
europepmc   +5 more sources

Serological and Pathogenic Analyses of Fowl Adenovirus Serotype 4 (FAdV-4) Strain in Muscovy Ducks. [PDF]

Front Microbiol, 2018
Hydropericardium hepatitis syndrome (HHS) is a lethal disease caused by Fowl adenovirus serotype 4(FAdV-4) that mainly infects 3- to 6-week-old broiler chicks. In 2015, an infectious disease characterized similar symptom to HHS in broilers outbroke in commercial duck flocks in Shandong province.
Yu X, Wang Z, Chen H, Niu X, Dou Y, Yang J, Tang Y, Diao Y.   +7 more
europepmc   +6 more sources

Designing a Novel Multi-Epitope Trivalent Vaccine Against NDV, AIV and FAdV-4 Based on Immunoinformatics Approaches. [PDF]

Microorganisms
The diseases caused by genotype VII Newcastle disease virus (NDV), H9N2 avian influenza virus (AIV), and fowl adenovirus serotype 4 (FAdV-4) continue to threaten the global poultry industry. However, no broad-spectrum vaccines provide simultaneous protection against these three pathogens.
Ji J, Dong X, Liu X, Ding M, Lin Y, Zhang Y, Zhang W, Lei B, Yuan W, Zhao K.   +9 more
europepmc   +4 more sources

Requirement of Cellular Protein CCT7 for the Replication of Fowl Adenovirus Serotype 4 (FAdV-4) in Leghorn Male Hepatocellular Cells Via Interaction with the Viral Hexon Protein

Viruses, 2019
Fowl adenovirus serotype 4 (FAdV-4) causes hepatitis-hydropericardium syndrome (HHS), leading to severe economic losses in the poultry industry. Although the pathogenesis of FAdV-4 infection has caused much attention, the underlying molecular mechanisms ...
Junfeng Gao, Mingliang Zhao, Xueyan Duan, Yongqiang Wang, Hong Cao, Xiaoqi Li, Shijun J. Zheng   +6 more
doaj   +2 more sources

A Novel Composite Vaccine Combining Inactivated Antigen and IgY Elicits Sustained Humoral Immunity Against FAdV-4 Viruses and PEDV Viruses. [PDF]

Viruses
Vaccination remains the primary strategy for controlling infectious diseases in farm animals. However, current conventional vaccines demonstrate clinical limitations including suboptimal immunogenicity and frequent booster requirements, which compromise disease management efficacy.
Gao W, Huang Z, Liu L, Li L, Huang H, Liu J, Zhou W, Song Y, Li X.   +8 more
europepmc   +4 more sources

Transcriptome analysis reveals critical factors for survival after adenovirus serotype 4 infection [PDF]

Poultry Science, 2023
: Fowl adenovirus serotype-4 (FAdV-4) is highly lethal to poultry, making it one of the leading causes of economic losses in the poultry industry. However, a small proportion of poultry can survive after FAdV-4 infection.
Yuhang Zhou, Qi Zheng, Shipeng Wang, Zhouyu Fu, Liang Hong, Wenjuan Qin, Qian Huang, Tingting Li, Yuhang Zhang, Cong Han, Daosong Chen, Hongquan Chen, Martin. F Bachmann, Lisha Zha, Jian Hao   +14 more
doaj   +2 more sources

Fowl Adenovirus 4 (FAdV-4)-Based Infectious Clone for Vaccine Vector Development and Viral Gene Function Studies [PDF]

Viruses, 2018
Fowl adenovirus 4 (FAdV-4) is associated with economically important poultry diseases. Recent studies of fully sequenced genomes of FAdV-4 isolates suggest potential genomic regions associated with virulence and amenable for manipulation and vector development.
Pei, Yanlong, Corredor, Juan, Griffin, Bryan, Krell, Peter, Nagy, Éva   +4 more
openaire   +4 more sources

Integrating Serological and Molecular Data to Characterize Fowl Adenovirus Associated With Inclusion Body Hepatitis in Broiler Chickens From Malaysia. [PDF]

Vet Med Sci
This study revealed the active circulation of fowl adenoviruses in broiler farms in Sabah, Malaysia. FAdV‐8b and FAdV‐11 were identified in flocks with IBH lesions, accompanied by high antibody titres in unvaccinated birds. Phylogenetic analysis showed close relationships with global strains, highlighting the need for enhanced surveillance and control ...
Bhuiyan MSA, Nath BK, Sam LM, Balakrishnan KN, Gupta SD, Sarker S.   +5 more
europepmc   +2 more sources

Molecular characterization and phylogenetic analysis of fowl adenovirus serotype-4 from Guangdong Province, China [PDF]

Veterinary World, 2020
Aim: Our aim in this study was to isolate potentially novel strains of fowl adenovirus serotype-4 (FAdV-4) that is currently circulating in broiler chicken flocks in Guangdong Province, China, and to compare nucleotide and amino acid (AA) sequences of ...
Fu Yuming, Yuan Sheng, Deng Wenyu, Chi Shihong, Li Wenfeng, Huang Wenjing, Li Xiaowen, Saeed El-Ashram, Kun Mei, Guo Jinyue, Zhang Xuelian, Li Zhili, Huang Shujian   +12 more
doaj   +3 more sources