A Novel Recombinant FAdV-4 Virus with Fiber of FAdV-8b Provides Efficient Protection against Both FAdV-4 and FAdV-8b [PDF]
Viruses, 2022 Since 2015, the outbreaks of hydropericardium-hepatitis syndrome (HHS) and inclusion body hepatitis (IBH) caused by the highly pathogenic serotype 4 fowl adenovirus (FAdV-4) and serotype 8 fowl adenovirus (FAdV-8), respectively, have caused huge economic
Hao Lu, Quan Xie, Zhehong Zhao
exaly +7 more sources
FAdV-4 without Fiber-2 Is a Highly Attenuated and Protective Vaccine Candidate [PDF]
Microbiology Spectrum, 2022 Hepatitis-hydropericardium syndrome (HHS) caused by the highly pathogenic fowl adenovirus serotype 4 (FAdV-4) has resulted in huge economic losses to the poultry industry globally.
Quan Xie, Luyuan Li, Tuofan Li
exaly +6 more sources
FAdV-4 induces more severe inflammatory responses compared to FAdV-8b [PDF]
Poultry ScienceMultiple infections, either single or mixed, involving pathogens such as serotype 4 fowl adenovirus (FAdV-4) and serotype 8b fowl adenovirus (FAdV-8b), have been observed in numerous laying hens in China, leading to severe liver damage.
Sidang Liu
exaly +7 more sources
Prevalence and Molecular Characteristics of FAdV-4 from Indigenous Chicken Breeds in Yunnan Province, Southwestern China [PDF]
Microorganisms, 2023 Fowl adenovirus-induced hepatitis–pericardial effusion syndrome outbreaks have been increasingly reported in China since 2015, resulting in substantial economic losses to the poultry industry. The genetic diversity of indigenous chicken results in different immune traits, affecting the evolution of these viruses.
Xiang Bin
exaly +6 more sources
Efficient cross-protection against serotype 4/8a fowl adenoviruses (FAdVs): recombinant FAdV-4 with FAdV-8a Fiber [PDF]
Microbiology Spectrum, 2023 Recently, the infection of fowl adenoviruses (FAdVs) in chicken flocks has caused huge economic losses to the poultry industry in China. Although immunization with Fiber protein can provide autogenous protection of FAdVs, no commercial multivalent ...
Tuofan Li, Zhimin Wan, Hongxia Shao
exaly +6 more sources
FAdV-4 Promotes Expression of Multiple Cytokines and Inhibits the Proliferation of aHEV in LMH Cells [PDF]
Viruses, 2023 Single or mixed infections of multiple pathogens such as avian hepatitis E virus (aHEV) and avian leukosis virus subgroup J (ALV-J) have been detected in numerous laying hens with severe liver injury in China. Thus, aHEV and immunosuppressive viruses are
Lidan Hou, Yawen Zhang, Zhang Yawen
exaly +6 more sources
The complete genome sequence of a new fowl adenovirus (Fadv-4) strain from a recent outbreak in a chicken farm in Iran [PDF]
Microbiology Resource AnnouncementsABSTRACT The whole genomic sequence of fowl adenovirus C (FAdV-4) strain FAdV-4/Pasouk, isolated from chickens with hepatitis-hydropericardium syndrome (HHS) from an outbreak in Iran, has been deposited in GenBank under accession number ON652872 .
Aliakbar Khabiri +2 more
exaly +5 more sources
FAdV-4 can cause more noticeable clinical symptoms compared to FAdV-8b after infecting specific pathogen free chickens [PDF]
Poultry Science: Chickens infected with FAdV-4 and FAdV-8b both exhibit hepatic lesions characterized by hemorrhagic necrosis and intranuclear inclusion body formation. However, only FAdV-4 induces pericardial effusion and acute mortality in chickens.
Yunfei Huang, Sidang Liu
exaly +6 more sources
Two novel monoclonal antibodies against fiber-1 protein of FAdV-4 and their application in detection of FAdV-4/10 [PDF]
BMC Veterinary Research, 2019 Background Recently, serotype 4 fowl adenovirus (FAdV-4) has spread widely and caused huge economic loss to poultry industry. However, little is known about the molecular pathogenesis of FAdV-4.
Hongxia Shao +9 more
doaj +4 more sources
Hypervirulent FAdV-4 infection induces activation of the NLRP3 inflammasome in chicken macrophages [PDF]
Poultry Science, 2022 : Fowl adenovirus serotype 4 (FAdV-4) is the primary causative agent of hepatitis–hydropericardium syndrome (HHS) causing great economic losses to the world poultry industry. The exact factors responsible for the pathogenesis of hypervirulent FAdV-4 have
Baiyu Wang +10 more
doaj +4 more sources