An optimized sandwich ELISA for quantitative detection of fowl adenovirus serotype 4 (FAdV-4) in chickens [PDF]
Fowl adenovirus serotype 4 (FAdV-4) causes hydropericardium-hepatitis syndrome (HHS) in chickens, resulting in severe economic losses worldwide. Fast and accurate diagnostic methods for FAdV-4 are required to monitor its prevalence and provide plausible ...
Huimin Ma +7 more
doaj +5 more sources
Prevalence and Molecular Characteristics of FAdV-4 from Indigenous Chicken Breeds in Yunnan Province, Southwestern China [PDF]
Fowl adenovirus-induced hepatitis–pericardial effusion syndrome outbreaks have been increasingly reported in China since 2015, resulting in substantial economic losses to the poultry industry. The genetic diversity of indigenous chicken results in different immune traits, affecting the evolution of these viruses.
Lai J +11 more
exaly +6 more sources
Two novel monoclonal antibodies against fiber-1 protein of FAdV-4 and their application in detection of FAdV-4/10 [PDF]
Background Recently, serotype 4 fowl adenovirus (FAdV-4) has spread widely and caused huge economic loss to poultry industry. However, little is known about the molecular pathogenesis of FAdV-4.
Hongxia Shao +9 more
doaj +5 more sources
The complete genome sequence of a new fowl adenovirus (Fadv-4) strain from a recent outbreak in a chicken farm in Iran [PDF]
ABSTRACT The whole genomic sequence of fowl adenovirus C (FAdV-4) strain FAdV-4/Pasouk, isolated from chickens with hepatitis-hydropericardium syndrome (HHS) from an outbreak in Iran, has been deposited in GenBank under accession number ON652872 .
Phuong Thi Kim Doan +2 more
exaly +5 more sources
Design and Identification of a Novel Antiviral Affinity Peptide against Fowl Adenovirus Serotype 4 (FAdV-4) by Targeting Fiber2 Protein. [PDF]
Outbreaks of hydropericardium hepatitis syndrome caused by fowl adenovirus serotype 4 (FAdV-4) with a novel genotype have been reported in China since 2015, with significant economic losses to the poultry industry. Fiber2 is one of the important structural proteins on FAdV-4 virions.
Chen X +10 more
europepmc +5 more sources
Pathogenicity of an FAdV-4 isolate to chickens and its genomic analysis [PDF]
Fowl adenovirus serotype 4 (FAdV-4) strain SD1511 was isolated from chickens with severe inclusion body hepatitis and hydropericardium syndrome in Shandong Province, China. The isolate was cultured in primary chicken embryo kidney cells. A study of pathogenicity indicated that SD1511 readily infected 7-35-d-old chickens by intramuscular injection and ...
Kai-Kun Mo, Min Liao, Gang Xing
exaly +5 more sources
Rapid detection of FAdV-4 by one-tube RPA-CRISPR/Cas12a assay. [PDF]
IntroductionFowl adenovirus serotype 4 (FAdV-4) is a highly contagious viral pathogen of global significance that affects various avian species. It primarily infects poultry and wild birds, leading to avian inclusion body hepatitis (IBH) and hepatitis-hydropericardium syndrome (HHS).
Ma L, Wang X, Zhang M, Zhu M.
europepmc +6 more sources
Residue 188 of the Hexon protein governs FAdV-4 pathogenicity by activating PINK1/Parkin-mediated mitophagy. [PDF]
Abstract Fowl adenovirus serotype 4 (FAdV-4) infection causes significant economic losses to the global poultry industry. Viruses often hijack host cellular machinery to facilitate their replication; however, the mechanisms by which FAdV-4 manipulates host pathways remain poorly defined.
Wang B +11 more
europepmc +3 more sources
Development of a Multiplex Conventional PCR Assay for Concurrent Detection of FAdV-4, FAdV-8b, and FAdV-11. [PDF]
Fowl adenovirus (FAdV) belongs to the Aviadenovirus genus within the Adenoviridae family. FAdVs are widely distributed and associated with various diseases in poultry, including adenoviral gizzard erosion (AGE), hepatitis-hydropericardium syndrome (HHS), and inclusion body hepatitis (IBH).
Kang SK +5 more
europepmc +5 more sources
Acclimation of suspension LMH cell line for high-efficient inactivated FAdV-4 vaccine production. [PDF]
Fowl adenovirus serotype 4 (FAdV-4) is the main pathogen of hepatitis-hydropericardium syndrome (HHS) and mainly prevented and controlled through inactivated vaccine vaccination. In this study, to improve manufacturing efficiency and quality of inactivated virus vaccine, adherent Leghorn Male Hepatoma cell line (LMH-TB) was adapted to suspension growth
Zhang H, Liao M, Gao X, Xue X, Cao H.
europepmc +5 more sources

