Results 31 to 40 of about 12,747,404 (156)

A novel monoclonal antibody efficiently blocks the infection of serotype 4 fowl adenovirus by targeting fiber-2

Veterinary Research, 2018
A recent outbreak of hepatitis–hydropericardium syndrome caused by serotype 4 fowl adenovirus (FAdV-4) has resulted in significant economic losses to the poultry industry worldwide. However, little is known about the molecular pathogenesis of FAdV-4.
Ping Wang, Jianjun Zhang, Weikang Wang, Tuofan Li, Guangchen Liang, Hongxia Shao, Wei Gao, Aijian Qin, Jianqiang Ye   +8 more
doaj   +2 more sources

Baculovirus-expressed FAdV-4 penton base protein protects chicken against hepatitis-hydropericardium syndrome

Journal of Integrative Agriculture, 2019
Hepatitis-hydropericardium syndrome (HHS) is an infectious disease caused by fowl adenovirus serotype 4 (FAdV-4). Several structural and non-structural proteins of FAdV-4 have been expressed in Escherichia coli and baculovirus expression system to develop candidate subunit vaccines.
Jun-qin ZHANG, Yan-ming WEI, Kun HUANG, Xiao-mei SUN, Zhong ZOU, Mei-lin JIN   +5 more
openaire   +3 more sources

A novel monoclonal antibody differentiates highly pathogenic serotype 4 fowl adenovirus through targeting 188R in the Hexon

Poultry Science
Since 2015, hepatitis-hydropericardium syndrome (HHS) induced by the infection of highly pathogenic serotype 4 fowl adenovirus (HP-FAdV-4) has caused severe economic losses to the poultry industry.
Ye Tang, Bai Xie, Shi Liu, Quan Xie, Weikang Wang, Junpeng Chen, Xiaoyan Tian, Junji Gan, Tuofan Li, Shengnan Wang, Zhimin Wan, Hongxia Shao, Aijian Qin, Jianqiang Ye   +13 more
doaj   +2 more sources

Differential innate immune responses to fowl adenovirus serotype 4 infection in Leghorn male hepatocellular and chicken embryo fibroblast cells

Poultry Science
: Fowl adenovirus serotype 4 (FAdV-4) infections result in substantial economic losses in the poultry industry. Recent findings have revealed that FAdV-4 significantly suppresses the host immune response upon infection; however, the specific viral and ...
Xiaolan Hou, Lizhen Wang, Riteng Zhang, Gen Liu, Ting Wang, Bo Wen, Wenchi Chang, Shuizhong Han, Jinjie Han, Junyang Fang, Xuefeng Qi, Jingyu Wang   +11 more
doaj   +2 more sources

Genetic characterization of novel fowl aviadenovirus 4 isolates from outbreaks of hepatitis-hydropericardium syndrome in broiler chickens in China

Emerging Microbes and Infections, 2016
Since May 2015, severe outbreaks of hepatitis-hydropericardium syndrome (HHS) associated with infections of fowl aviadenovirus (FAdV) have emerged in broiler chickens in several Chinese provinces.
Yanke Liu, Wenyan Wan, Dongsheng Gao, Yongtao Li, Xia Yang, Hongying Liu, Huixia Yao, Lu Chen, Chuanqing Wang, Jun Zhao   +9 more
doaj   +2 more sources

Biological features of fowl adenovirus serotype-4 [PDF]

Frontiers in Cellular and Infection Microbiology
Fowl adenovirus serotype 4 (FAdV-4) is highly pathogenic to broilers aged 3 to 5 weeks and has caused considerable economic loss in the poultry industry worldwide.
Farooq Rashid, Farooq Rashid, Farooq Rashid, Zhixun Xie, Zhixun Xie, Zhixun Xie, You Wei, You Wei, You Wei, Zhiqin Xie, Zhiqin Xie, Zhiqin Xie, Liji Xie, Liji Xie, Liji Xie, Meng Li, Meng Li, Meng Li, Sisi Luo, Sisi Luo, Sisi Luo   +20 more
doaj   +2 more sources

TMT-based quantitative proteomics analysis reveals the role of Notch signaling in FAdV-4-infected LMH cell. [PDF]

Front Microbiol, 2022
Fowl adenovirus serotype 4 (FAdV-4) is recognized as a pathogen that causes hydropericardium syndrome. Irrespective of the pathway used by the virus to invade the chicken, the pathological characteristics of the disease include degeneration and necrosis of hepatocytes, formation of intranuclear inclusions, as well as inflammatory cell infiltration ...
Niu Y, Liu Z, Wang M, Du K, Chang K, Ding Y.   +5 more
europepmc   +4 more sources

Mechanistic insights into the kidney injury in chickens induced by hypervirulent fowl adenovirus serotype 4

Microbiology Spectrum
Hypervirulent fowl adenovirus serotype 4 (FAdV-4) has emerged as a significant poultry pathogen since 2015, exhibiting clinical multi-organ and multi-tissue tropism post-infection, resulting in substantial economic losses in the poultry industry. However,
Chunhua Zhu, Jiayu Zhou, Zhen Chen, Cuiteng Chen, Ziyue Wang, Pei Yang, Guanghua Fu, Xiaodong Liu, Yu Huang, Chunhe Wan   +9 more
doaj   +2 more sources

Dual-expression-site fowl adenovirus 4 (FAdV-4) with high viral titer: a promising viral vector for multivalent poultry vaccines. [PDF]

Vet Res
Fowl adenovirus serotype 4 (FAdV-4) is a nonenveloped double-stranded DNA virus with a 43–45 kb genome, making it a promising viral vector for developing multivalent poultry vaccines.
Tang Z, Liu W, Xu B, Feng D, Liu S, Fan W, Song S, Yan L.   +7 more
europepmc   +2 more sources

Fiber-1 of serotype 4 fowl adenovirus mediates superinfection resistance against serotype 8b fowl adenovirus

Frontiers in Microbiology, 2022
In recent years, hepatitis-hydropericardium syndrome (HHS) and inclusion body hepatitis (IBH) caused by serotype 4 fowl adenovirus (FAdV-4) and serotype 8b fowl adenovirus (FAdV-8b), respectively, are widely prevalent in China, causing huge economic ...
Hao Lu, Hao Lu, Hao Lu, Hao Lu, Yiwen Guo, Yiwen Guo, Yiwen Guo, Yiwen Guo, Zhenqi Xu, Zhenqi Xu, Zhenqi Xu, Zhenqi Xu, Weikang Wang, Weikang Wang, Weikang Wang, Weikang Wang, Mingjun Lian, Mingjun Lian, Mingjun Lian, Mingjun Lian, Tuofan Li, Tuofan Li, Tuofan Li, Tuofan Li, Zhimin Wan, Zhimin Wan, Zhimin Wan, Zhimin Wan, Hongxia Shao, Hongxia Shao, Hongxia Shao, Hongxia Shao, Aijian Qin, Aijian Qin, Aijian Qin, Aijian Qin, Quan Xie, Quan Xie, Quan Xie, Quan Xie, Jianqiang Ye, Jianqiang Ye, Jianqiang Ye, Jianqiang Ye   +43 more
doaj   +1 more source