Results 71 to 80 of about 8,833,991 (337)

Long-term trajectory of estimated glomerular filtration rate in ambulatory patients with type 2 diabetes and heart failure: clinical insights and prognostic implications

Cardiovascular Diabetology
Background Although previous studies have evaluated renal function decline in patients with heart failure (HF), there is limited evidence on long-term renal trajectories, especially in patients with concomitant HF and type 2 diabetes (T2D).
Maria Teresa Julián, Pau Codina, Josep Lupón, Elisabet Zamora, Alejandra Pérez-Montes de Oca, Mar Domingo, Evelyn Santiago-Vacas, Andrea Borrellas, María Ruiz-Cueto, Carlos González-Gallego, Maribel Troya, Gregorio A. Romero-González, Nuria Alonso, Antoni Bayes-Genis   +13 more
doaj   +1 more source

Mycophenolate mofetil versus cyclophosphamide for idiopathic membranous nephropathy; a double blind and randomized clinical trial [PDF]

Journal of Nephropathology, 2019
Introduction: The current treatment regimens for patients with idiopathic membranous nephropathy (MN) are based on cyclophosphamide-glucocorticoid or calcineurin inhibitor-glucocorticoid.
Fatemeh Hayati, Heshmatollah Shahbazian, Ali Ghorbani, Shahla Ahmadi Halili, Eisa Rezaei, Leila Sabetnia, Seyed Seifollah Beladi Mousavi   +6 more
doaj   +1 more source

Temporal-varying failures of nodes in networks

, 2015
We consider networks in which random walkers are removed because of the failure of specific nodes. We interpret the rate of loss as a measure of the importance of nodes, a notion we denote as failure-centrality. We show that the degree of the node is not
Altmann, Eduardo G., Cristadoro, Giampaolo, Knight, Georgie   +2 more
core   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Perfectionism and self-conscious emotions in British and Japanese students: Predicting pride and embarrassment after success and failure [PDF]

, 2013
Regarding self-conscious emotions, studies have shown that different forms of perfectionism show different relationships with pride, shame, and embarrassment depending on success and failure.
Benson E., Brislin R. W., Cohen J., Dunkley D. M., Edelstein R. S., Enns M. W., Fee R. L., Flett G. L., Hewitt P. L., Home Office, Joachim Stoeber, Kitayama S., Kitayama S., Klibert J. J., Markus H. R., Nunnally J. C., Ohtani K., Osamu Kobori, Preacher K. J., Slaney R. B., Tabachnick B. G., Tangney J. P., Tangney J. P., Tracy J. L., Triandis H. C., Triandis H. C., Wong Y., Yoshihiko Tanno   +27 more
core   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Inverter ratio failure detector [PDF]

, 1974
A failure detector which detects the failure of a dc to ac inverter is disclosed. The inverter under failureless conditions is characterized by a known linear relationship of its input and output voltages and by a known linear relationship of its input ...
Andrews, R. E., Ebersole, T. J., Wagner, A. P.   +2 more
core   +1 more source

Failure characteristics of all polyethylene cemented glenoid implants in total shoulder arthroplasty [PDF]

, 2010
Total shoulder arthroplasty (TSA) still suffers today from mid-term and long-term complications such as glenoid implant loosening, wear, humeral head subluxation/dislocation and implant fracture. Unlike the hip and knee joint replacements, the artificial
Junaid, Sarah, Junaid, Sarah
core   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source