Results 61 to 70 of about 266,152 (301)

Serum Myonectin Levels Are Positively Associated With Physical Function and Lower Frailty‐Related Limitation in Maintenance Hemodialysis Patients: A Cross‐Sectional Study

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Maintenance hemodialysis (MHD) patients frequently suffer from frailty, characterized by reduced physical function and poor prognosis. Myokines, such as myonectin, secreted by muscle, are emerging regulators of systemic health. This study investigated the relationship between serum myonectin, adipokines (adiponectin, omentin), and ...
Kenichi Kono   +7 more
wiley   +1 more source

Simple evaluation method of adhesive failure criterion in multiaxial stress states by uniaxial tensile tests

open access: yesMechanical Engineering Journal, 2018
We propose a simple tensile test with which to identify the parameters that constitute the failure criterion of an adhesive in a multiaxial stress state. In this paper, we define the failure criterion as the proportional limit of load-displacement curves
Masato IIMORI   +4 more
doaj   +1 more source

A Criterion on Fatigue Failure of Metals

open access: yesTransactions of the Japan Society of Mechanical Engineers, 1956
There has been some difficulties in explaining compression endurance limit diagram, by preceeding fatigue criteria. The authors propose a new criterion and show that this can explain the compression endurance limit diagram. In this criterion they consider that the material is fatigued by the stress amplitude of the repeated shearing stress and the ...
KAWADA, Yuichi, KODAMA, Shotaro
openaire   +2 more sources

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Characterising plastic collapse of pipe bend structures

open access: yes, 2006
Two recently proposed design by analysis criteria of plastic collapse based on plastic work concepts, the plastic work (PW) criterion and the plastic work curvature (PWC) criterion, are applied to a strain hardening pipe bend arrangement subject to ...
Li, Hongjun, Mackenzie, Donald
core   +1 more source

Mechanical Properties of Post-Filling Coarse Aggregate Concrete under Biaxial Tension–Compression

open access: yesBuildings
Post-filling coarse aggregate concrete (PFCC) is a new type of concrete that achieves energy-saving and emission-reduction goals through optimizing material proportions.
Jinqing Jia, Lu Li, Wei Liu
doaj   +1 more source

Clinical characteristics of emergency department heart failure patients initially diagnosed as non-heart failure

open access: yesBMC Emergency Medicine, 2006
Background Since previous studies suggest the emergency department (ED) misdiagnosis rate of heart failure is 10–20% we sought to describe the characteristics of ED patients misdiagnosed as non-decompensated heart failure in the ED. Methods We analyzed a
Eckert Daniel C   +5 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

A critical appraisal of the Hashin failure criterion

open access: yes
The Hashin criterion is one the most popular failure criteria for fibre reinforce composites. It is critically appraised in this paper. The most significant feature of the criterion is failure modes introduced and the assumption that failure is ...
Li, Shuguang, Sitnikova, Elena
core   +1 more source

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