Results 71 to 80 of about 266,152 (301)
Failure analysis of carbon fiber reinforced composite countersunk bolt joint
In order to study the initiation, propagation and material failure behavior of T800 carbon fiber reinforced composite joint structure with countersunk bolt under load, the quasi-static tensile tests were carried out on the bolt joint structure. The three-
WANG Qiang +4 more
doaj +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Study on Aircraft Reliability Assessment in Flight Test and Service Period
The reliability level is one of the most significant indexes to be considered in aircraft design process. In order to guarantee the objectivity and accuracy of results, the study on aircraft reliability assessment in flight test and service period is ...
GUO Peng, ZHAO Xiaodong
doaj +1 more source
A General Failure Criterion for Frictional and Cohesive Materials
ABSTRACT The Matsuoka-Nakai failure criterion for a frictional material, and the Von Mises criterion for a cohesive material are expressed in such a way that they are seen to bear similar relationships to the cohesionless Mohr-Coulomb and Tresca criteria respectively.
openaire +2 more sources
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Tensile membrane action (TMA) could significantly enhance the ultimate bearing capacity of reinforced concrete (RC) simply supported slabs under fire conditions.
Yan Jia +8 more
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
A New Criterion for Judging Tunnel Failure by the Strength Reduction Method
Recently, the application of the strength reduction method (SRM) to tunnel stability research has become a trend. The failure criteria for the SRM in tunnels often draw from those used in slopes.
Chengya Hua, Chenguang Song, Leihua Yao
doaj +1 more source
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
A generalized anisotropic failure criterion for geomaterials
Experimental evidence shows that the strength of geomaterials, such as soils and rocks, is significantly influenced by inherent anisotropy and other factors such as shear banding and the intermediate principal stress, which cannot be properly described ...
Yao, Yangping +5 more
core +1 more source

