Results 71 to 80 of about 268,710 (264)
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Cogent Engineering, 2016 The results of stress field distribution in damage cross-ply laminates prompt us to elaborate an energy criterion. This criterion is based on the partial parts’s computation of the strain energy release rate associated with each damage type and for all ...
Jean-Luc Rebière
doaj +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Implementation of a constitutive model for anisotropic rocks based on modified Lade failure criterion. [PDF]
Sci Rep, 2023 Liu X, Deng Y, Zou B.
europepmc +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Failure criterion for adhesively bonded joints using Arcan´s experimental method
Polímeros, 2014 Characterization of polymeric materials mechanical behavior requires some previous knowledge about their structure, which allows the choice of more appropriated models and methods.
Demetrio Jackson dos Santos +1 more
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Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Integration and Application of a Fabric-Based Modified Cam-Clay Model in FLAC3D
GeosciencesIn order to consider the effect of fabric anisotropy in the analysis of geotechnical boundary value problems, this study proposes a modified model based on a fabric-based modified Cam-clay model, which can account for the anisotropic response of soil ...
Xiao-Wen Wang +5 more
doaj +1 more source
Mechanical Engineering Journal, 2018 We propose a simple tensile test with which to identify the parameters that constitute the failure criterion of an adhesive in a multiaxial stress state. In this paper, we define the failure criterion as the proportional limit of load-displacement curves
Masato IIMORI +4 more
doaj +1 more source