Results 121 to 130 of about 1,246,486 (311)

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Healthcare Failure Mode and Effect Analysis in Surgery Setting: A Bibliometrics Analysis and Literature Review. [PDF]

Acta Inform Med, 2023
Sumarwoto T, Ilyas MF, Dewi A.
europepmc   +1 more source

Independent Orbiter Assessment (IOA): Analysis of the landing/deceleration subsystem [PDF]

The results of the Independent Orbiter Assessment (IOA) of the Failure Modes and Effects Analysis (FMEA) and Critical Items List (CIL) are presented. The IOA approach features a top-down analysis of the hardware to determine failure modes, criticality ...
Beaird, H. G., Compton, J. M., Weissinger, W. D.   +2 more
core   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Application of healthcare failure mode and effect analysis in controlling surgical instrument packaging defects. [PDF]

Sci Rep, 2022
Yi L, Chen Y, Hu R, Hu J, Pan W.
europepmc   +1 more source

Advanced approaches to failure mode and effect analysis (FMEA) applications

Metalurgija, 2015
The present paper explores advanced approaches to the FMEA method (Failure Mode and Effect Analysis) which take into account the costs associated with occurrence of failures during the manufacture of a product. Different approaches are demonstrated using
D. Vykydal, J. Plura, P. Halfarová, P. Klaput   +3 more
doaj  

Aplikasi Metode Taguchi Analysis Dan Failure Mode and Effect Analysis (Fmea) Untuk Perbaikan Kualitas Produk Di PT. Xyz [PDF]

, 2013
PT. XYZ merupakan Perusahaan yang bergerak dibidang produksi lolly dan cup plastik. Produk lolly yang dihasilkan oleh Perusahaan ini sering mengalami kecacatan dan tidak sesuai dengan standar yang telah ditetapkan, bahkan jumlah produk cacat melebihi ...
Ginting, E. (Elisabeth), Iswanto, A. (Adi), M. Rambe, A. Jabbar   +2 more
core  

Nonlinear Analysis of Reinforced Concrete Beams using FEM with Smeared Crack Approach, Mohr’s Failure Criteria, and The Tomaszewicz Model

, 2008
Cracking has a predominant effect on the failure mode of reinforced concrete beams. Their presence results a nonlinear stiffness behavior. Previous research work explained the concrete cracking process due to the exceeding of the major tensile principal ...
Braunstein, Pierre, Cazin, Catherine S.J., Diebolt, Olivier, Nolan, Steven Patrick   +3 more
core   +2 more sources

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Failure mode and effect analysis for linear accelerator-based paraspinal stereotactic body radiotherapy. [PDF]

J Appl Clin Med Phys, 2021
Lee S, Lovelock DM, Kowalski A, Chapman K, Foley R, Gil M, Pastrana G, Higginson DS, Yamada Y, Zhang L, Mechalakos J, Yorke E.   +11 more
europepmc   +1 more source