Results 91 to 100 of about 1,169,414 (346)

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Risk Analysis by Failure Modes, Effects and Criticality Analysis and Biosafety Management During Collective Air Medical Evacuation of Critically Ill Coronavirus Disease 2019 Patients [PDF]

, 2021
Lionel Koch, Olivier Nespoulous, Jean Turc, Cyril Linard, P. Martigne, Madeleine Beaussac, Sophie Murris, Olivier Ferraris, Marc Grandadam, Gaelle Frénois-Veyrat, Anne‐Aurélie Lopes, Mathieu Boutonnet, Fabrice Biot   +12 more
openalex   +1 more source

Risk Factor Assessment in a Carpet Manufacturing Company Using the Failure Modes and Effects Analysis in Mazandaran

تحقیقات سلامت در جامعه, 2019
Introduction and purpose: The most prevalent accidents and injuries occur in industries. Risk assessment and risk management are the basis for planning to provide solutions and control hazards.
solale ramzani, mirtaghi mirmohammadi
doaj  

Production Improvement through Fixture Design: A Case Study of an Agricultural Machinery Parts Manufacturer

RMUTL Engineering Journal
This case study focuses on a manufacturing company producing agricultural machinery parts. The company faced a significant challenge: it could not meet customer demand due to inefficiencies in the production process.
Bhoomboon Phontang, Jetnipat Pimollukanakul, Thamrong Gearam, Jittiwat Nithikarnjanatharn, Supattra Muparang, Wannisa Nutkhum   +5 more
doaj   +1 more source

Geometrically nonlinear analysis of adhesively bonded joints [PDF]

A geometrically nonlinear finite element analysis of cohesive failure in typical joints is presented. Cracked-lap-shear joints were chosen for analysis.
Dattaguru, B., Everett, R. A., Jr., Johnson, W. S., Whitcomb, J. D.   +3 more
core   +1 more source

Journal Staff [PDF]

, 2011
Riskanalysverktyget failure mode and effects analysis (FMEA) som analyserar kompo-nenter och signaler är beroende av att designen av fordonets elsystem finns tillgängligt och utförs därför sent i utvecklingsprocessen av elsystem.
Baitar, Rami
core   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

Application of Failure Mode, Effects, and Criticality Analysis to the Medication-Use Process for Temperature-Sensitive Drugs in a University Hospital

, 2022
Hana Sakly, Inès Chakroun, K. Ben Jeddou   +2 more
openalex   +2 more sources

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

Molecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola, Rafael Lopes Goncalves, Marin Truchi, Caroline Lacoux, Célia Scribe, Hugo Cadis, Laetitia Guardini, Sophie Bekisz, Marius Ilié, Paul Hofman, Georges Vassaux, Bernard Mari, Roger Rezzonico   +12 more
wiley   +1 more source

Use of failure mode and effects analysis in improving the safety of i.v. drug administration [PDF]

, 2005
Wayne Adachi, Amy E. Lodolce
openalex   +1 more source