Failure mode and effects analysis

Results 71 to 80 of about 247,951 (252)

A novel decision-making approach for risk assessment of converter steelmaking process based on fuzzy DEMATEL method

Alexandria Engineering Journal
Converter steelmaking is a critical process in steel production, facing various failure modes with severe safety and operational risks. However, comprehensive risk assessments in this area remain limited.
Fei Gao, Ding Zhou
doaj +1 more source

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn +2 more
wiley +1 more source

Clinical Risk Assessment of Intensive Care Unit using Failure Mode and Effects Analysis

بیمارستان, 2015
Background: The goal of clinical risk management is to improve the quality of health care organization’s services and to ensure patientschr('39') safety.
Farnaz Attar Jannesar Nobari +3 more
doaj

Production Improvement through Fixture Design: A Case Study of an Agricultural Machinery Parts Manufacturer

RMUTL Engineering Journal
This case study focuses on a manufacturing company producing agricultural machinery parts. The company faced a significant challenge: it could not meet customer demand due to inefficiencies in the production process.
Bhoomboon Phontang +5 more
doaj +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source

Risk Factor Assessment in a Carpet Manufacturing Company Using the Failure Modes and Effects Analysis in Mazandaran

تحقیقات سلامت در جامعه, 2019
Introduction and purpose: The most prevalent accidents and injuries occur in industries. Risk assessment and risk management are the basis for planning to provide solutions and control hazards.
solale ramzani, mirtaghi mirmohammadi
doaj

Enhancing patient care quality and safety under the hospital-wide “One Bed” model: a FMEA-based approach

Frontiers in Medicine
BackgroundThe hospital-wide “One Bed” model poses potential risks in cross-departmental patient care, affecting nursing quality and patient safety. However, systematic evaluation and improvement strategies for these risks remain limited.ObjectiveThis ...
Xixi Li +7 more
doaj +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens +2 more
wiley +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source

failure mode and effects analysis fmea
risk assessment
3. good health

risk management
fmea
risk priority number

humans
healthcare failure mode and effects analysis
patient safety