Results 61 to 70 of about 262,049 (253)
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Real-time monitoring of methane (CH₄) and carbon dioxide (CO₂) in peatland simulation environments requires a reliable Internet of Things (IoT)-based monitoring platform.
Angela Irena Putri Sasmitha Dhanti +2 more
doaj +1 more source
Intelligent manufacturing is one of the indispensable parts in Industry 4.0, where the smart machines can perceive and operate automatically in production process to provide higher and more convenient efficiency.
Neng Wan, Lei Li, Chunming Ye, Bo Wang
doaj +1 more source
An Improved Failure Mode Effects Analysis for Hospitals
Abstract Objective. —To review the Failure Mode Effects Analysis (FMEA) process recommended by the Joint Commission on Accreditation of Health Organizations and to review alternatives. This reliability engineering tool may be unfamiliar to hospital personnel.
openaire +2 more sources
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Sensitivity Analysis plays a crucial role in the design, control, and optimization of multi-pulse Voltage Source Converters. It helps engineers assess how variations in parameters influence system performance, enabling the development of more efficient ...
A. Valderrabano-Gonzalez +5 more
doaj +1 more source
Effectiveness Of Failure Modes Effect Analysis (FMEA)
Objective : One of the prevention efforts of medical errors that occur in health services is by identifying the potential failure of the service before the failure occurs. FMEA is one way to identify the risks of failure. Therefore, the authors wanted to find out whether FMEA was effective for reducing Medical error based on previous studies.Method ...
Putri Ingen Setiasih, Purnawan Junadi
openaire +2 more sources
Translophagy—A potential link between autophagy impairment and translational errors
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Background and Aim: Operation rooms have several specialty processes, a higher level of technology, complicated treatment protocols, and the need for skillful human recourses, which is one of the highest risk wards in the hospital.
Sousan Rabihavy, Zhila Najafpour
doaj
Structural and biochemical analysis of a B12 superbinder
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source

