Results 61 to 70 of about 1,169,414 (346)

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

Risk Assessment of the Processes of Operating Room Department using the Failure Mode and Effects Analysis (FMEA) Method

بیمارستان, 2017
Background: Reduction of errors is necessary to improve the quality of healthcare, promoting communication between the hospital staff and patients, and decreasing the patientchr('39')s complaints in hospitals.
Zahra Kavosi, Fateme Setoodehzadeh, Mozhgan Fardid, Maryam Gholami, Marzie Khojastefar, Mahbube Hatam, Zahra tahiati, Gholamreza Fardid   +7 more
doaj  

Space tug propulsion system failure mode, effects and criticality analysis [PDF]

For purposes of the study, the propulsion system was considered as consisting of the following: (1) main engine system, (2) auxiliary propulsion system, (3) pneumatic system, (4) hydrogen feed, fill, drain and vent system, (5) oxygen feed, fill, drain ...
Boyd, J. W., Hardison, E. P., Heard, C. B., Orourke, J. C., Osborne, F., Wakefield, L. T.   +5 more
core   +1 more source

Reliability failure mode, effects, and criticality analysis : addendum 2 PSE [PDF]

, 1971
This addendum updates the System Failure Mode, Effects and Criticality Analysis (FMECA) for the Passive Seismic Experiment (PSE) Array A-2D, and E to the date of this addendum.prepared by R.W. Hiebert.B-
Hiebert, Robert W.
core  

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

Molecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath, Irene A. George, Srikanth S. Manda, Prasanth Ariyannur, Ekta R. Dhawale, Raja Sekhar Kommu, Rajan Datar, Darshana Patil, Vinita Trivedi, Manisha Singh, Kumar Prabhash, Sewanti Limaye, Richa Chauhan, Prashant Kumar   +13 more
wiley   +1 more source

A Novel Method for Failure Mode and Effect Analysis Based on the Fermatean Fuzzy Set and Bonferroni Mean Operator

Machines
Failure mode and effects analysis (FMEA) helps to identify the weak points in the processing, manufacturing, and assembly of products and plays an important role in improving product reliability.
Liangsheng Han, Mingyi Xia, Yang Yu, Shuai He   +3 more
doaj   +1 more source

Risk Assessment of the Operating Room Processes Using the Failure Mode, Effects, and Criticality Analysis (FMECA) Method: A Case Study

پیاورد سلامت, 2022
Background and Aim: Operation rooms have several specialty processes, a higher level of technology, complicated treatment protocols, and the need for skillful human recourses, which is one of the highest risk wards in the hospital.
Sousan Rabihavy, Zhila Najafpour
doaj  

Risk Assessment in Intelligent Manufacturing Process: A Case Study of an Optical Cable Automatic Arranging Robot

IEEE Access, 2019
Intelligent manufacturing is one of the indispensable parts in Industry 4.0, where the smart machines can perceive and operate automatically in production process to provide higher and more convenient efficiency.
Neng Wan, Lei Li, Chunming Ye, Bo Wang
doaj   +1 more source

Independent Orbiter Assessment (IOA): Analysis of the crew equipment subsystem [PDF]

The results of the Independent Orbiter Assessment (IOA) of the Failure Modes and Effects Analysis (FMEA) and Critical Items List (CIL) are presented. The IOA approach features a top-down analysis of the hardware to determine failure modes, criticality ...
Graham, L., Richard, Bill, Saxon, H., Sinclair, Susan   +3 more
core   +1 more source

Reliability based design of fluid power pitch systems for wind turbines [PDF]

, 2017
This paper presents a qualitative design tool for evaluation of the risk for fluid power pitch systems. The design tool is developed with special attention to industry standard failure analysis methods and is aimed at the early phase of system design ...
Arabian-Hoseynabadi, Atkinson, Bertsche, Carroll, Gjerstad, Global Wind Energy Council & Greenpeace International, Hogan, Hogan, Hunt, Isermann, Stapelberg, Totten, Watton, Wilkinson, Yang   +14 more
core   +2 more sources