Results 71 to 80 of about 2,001,528 (211)

Drug resistance outcomes of long-term ART with tenofovir disoproxil fumarate in the absence of virological monitoring [PDF]

, 2018
Objectives: The resistance profiles of patients receiving long-term ART in sub-Saharan Africa have been poorly described. This study obtained a sensitive assessment of the resistance patterns associated with long-term tenofovir-based ART in a ...
Appiah, Lambert T, Beloukas, Apostolos, Chadwick, David, Geretti, Anna Maria, Phillips, Richard O, Ruggiero, Alessandra, Sarfo, Fred S, Smith, Colette, Stockdale, Alexander J, Villa, Giovanni   +9 more
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Upward trends of acquired drug resistances in Ethiopian HIV-1C isolates: A decade longitudinal study.

PLoS ONE, 2017
BackgroundThe emergence, accumulation and spread of HIV-1 drug resistance strains in Africa could compromise the effectiveness of HIV treatment programs.
Andargachew Mulu, Melanie Maier, Uwe Gerd Liebert   +2 more
doaj   +1 more source

Porous titanium for biomedical applications : development, characterization and biological evaluation [PDF]

, 2007
Metallic biomaterials have so far shown the greatest potential to be the basis of implants for long-term load-bearing orthopedic and dental applications, owing to their excellent mechanical strength when compared to alternative biomaterials, such as ...
Li, JiaPing
core   +1 more source

Effect of load flank angle modifications on the structural integrity of buttress threaded connections [PDF]

, 2013
One of the main requirements of threaded & coupled connections used in oil-producing wells is the ability to resist high tensile loads. In order to ensure integrity under ever-increasing loads, the geometric parameters of the connection can be modified ...
De Baets, Patrick, De Waele, Wim, Galle, Timothy, Jula, Felicia Camelia, Van Wittenberghe, Jeroen   +4 more
core   +1 more source

Failure Mode Discrimination and Stochastic Behavior Study of RC Beams Under Impact Loads

Modelling
To clarify the potential failure modes of reinforced concrete (RC) beams under impact and understand their impact resistance safety, a comprehensive study was conducted by focusing on the failure mode discrimination and failure probability of RC beams ...
Taochun Yang, Yating Jiang, Xiaoyan Zhang, Qinghai Liu, Yin Wang   +4 more
doaj   +1 more source

Assessment and analysis of H.pylori infection treatment strategies of St. Vincent Hospital\u27s family and internal medicine clinics [PDF]

, 2019
Helicobacter pylori is a gram-negative bacteria that is responsible for causing chronic gastritis, ulcers in the stomach and intestine, and eventually even gastric lymphoma or cancer.
Orr, Rebecca
core   +1 more source

Soil resistance under pipe vertical uplift in compacted clay: shallow tensile and deep shear failure mechanisms

Journal of Pipeline Science and Engineering
The paper investigates the mobilization of soil resistance against pipe vertical uplift in compacted Regina clay using both physical and numerical modelling.
Chee K. Wong, Richard G. Wan, Ron C.K. Wong   +2 more
doaj   +1 more source

HIV-1 genotypic drug resistance in patients with virological failure to single-tablet antiretroviral regimens in southern Taiwan

Infection and Drug Resistance, 2018
Hung-Chin Tsai,1–3 I-Tzu Chen,1 Susan Shin-Jung Lee,1,2 Yao-Shen Chen1,2 1Division of Infectious Diseases, Department of Medicine, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan; 2Faculty of Medicine, School of Medicine, National Yang-Ming ...
Tsai HC, Chen IT, Lee SS, Chen YS
doaj  

Whole-genome sequencing and machine learning reveal key drivers of delayed sputum conversion in rifampicin-resistant tuberculosis

Frontiers in Cellular and Infection Microbiology
Rifampicin-resistant tuberculosis (RR-TB) remains a major global health challenge, with delayed sputum culture conversion (SCC) predicting poor treatment outcomes.
Qing Fang, Xiangchen Li, Xiangchen Li, Yewei Lu, Junshun Gao, Yvette Wu, Yi Chen, Yang Che   +7 more
doaj   +1 more source

Impact of Minority Nonnucleoside Reverse Transcriptase Inhibitor Resistance Mutations on Resistance Genotype After Virologic Failure [PDF]

, 2017
Drug-resistant human immunodeficiency virus type 1 (HIV-1) minority variants increase the risk of virologic failure for first-line nonnucleoside reverse transcriptase inhibitor (NNRTI)-based regimens.
Geretti, Anna Maria, Hullsiek, Katherine Huppler, Jakobsen, Martin R., Johnson, Jeffrey A., Kozal, Michael J., Kuritzkes, Daniel R., Li, Jonathan Z., Metzner, Karin J., Miller, Michael D., Ostergaard, Lars, Paredes, Roger, Ribaudo, Heather J., Svarovskaia, Evguenia S.   +12 more
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