Results 101 to 110 of about 2,278,950 (331)

Modeling the Initial Conditions of Interacting Galaxy Pairs Using Identikit

open access: yes, 2015
We develop and test an automated technique to model the dynamics of interacting galaxy pairs. We use Identikit (Barnes & Hibbard 2009, Barnes 2011) as a tool for modeling and matching the morphology and kinematics of the interacting pairs of equal-mass ...
Barnes, Joshua E.   +3 more
core   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

open access: yesMolecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié   +16 more
wiley   +1 more source

Chapter Three. EED library as a basis for systematic reviews [PDF]

open access: yes, 2016
3.1 Defining Systematic Review Question Priorities 3.2 Determining Relevance to the Systematic Review 3.3 Acquisition of References and Copyright Fair Use Compliance 3.4 Documenting Relevance to the Systematic Review 3.5 Data Extraction for the ...
Denno, Donna M   +4 more
core   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard   +5 more
wiley   +1 more source

'Fair Trade' Coffee and the Mitigation of Local Oligopsony Power [PDF]

open access: yes
In recent years there has been considerable growth in ‘Fair Trade’ markets for several commodities, but most notably for coffee. We argue that coffee is grown under conditions that might well subject growers to the market power of intermediaries.
Donald MacLaren   +2 more
core  

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

open access: yesMolecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He   +8 more
wiley   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

open access: yesMolecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia   +9 more
wiley   +1 more source

FAIR data

open access: yes
Goals Understand: what does FAIR data mean? apply: what does it really mean? Understand: data science pipeline and collaboration apply: looking into the „i“ and „r“ of FAIR Learning objectives The students can name and explain the special challenges of data science and its pipelines in the application area The students can explain ...
openaire   +2 more sources

Decentralised Semantics: A Semantic Engine User Perspective

open access: yesData Science Journal
The Findable, Accessible, Interoperable and Reusable (FAIR) data principles were created to guide the improvement of research data (Wilkinson et al., 2016). As data curators and educators, we often see individual research groups and researchers establish
Carly M. Huitema   +3 more
doaj   +1 more source

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