Results 131 to 140 of about 2,278,950 (331)

Open Science & FAIR Data

open access: yes, 2019
Presentation for the 1st EUSMI/NFFA-Europe Joint School on Data management: Trieste, 10-11 December ...
openaire   +2 more sources

Monitoring of circulating tumor DNA allows early detection of disease relapse in patients with operable breast cancer

open access: yesMolecular Oncology, EarlyView.
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad   +35 more
wiley   +1 more source

From Raw Data to FAIR Data: The FAIRification Workflow for Health Research [PDF]

open access: green, 2020
Ali Anıl Sınacı   +13 more
openalex   +1 more source

The Choice of Inequality Measure in Empirical Research on Distributive Judgements. [PDF]

open access: yes
We analyse questionnaire data from a representative sample of the Flemish working population. For 781 respondents we construct their perception of the actual and of the fair income distribution.
André Decoster, Erik Schokkaert
core  

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Can Racially Unbiased Police Perpetuate Long-Run Discrimination? [PDF]

open access: yes
We develop a stylized dynamic model of highway policing in which a non-racist police officer is given incentives to arrest criminals, but faces a per stop cost of stop which increases when the racial mix of the persons he stops di.ers from the racial mix
Bunzel, H., Marcoul, P.
core   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

A Data-Driven Approach to Monitor and Improve Open and FAIR Research Data in a Federated Research Ecosystem

open access: yesData Science Journal
In this contribution we present a data-driven approach to monitoring and assessing the state of open and FAIR data in an interdisciplinary, federated research ecosystem.
Markus Kubin   +9 more
doaj   +1 more source

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

open access: yesMolecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li   +10 more
wiley   +1 more source

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