Results 81 to 90 of about 3,690,597 (318)

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Repository Approaches to Improving the Quality of Shared Data and Code

open access: yesData, 2021
Sharing data and code for reuse has become increasingly important in scientific work over the past decade. However, in practice, shared data and code may be unusable, or published results obtained from them may be irreproducible. Data repository features
Ana Trisovic   +4 more
doaj   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

Harmonizing quality measures of FAIRness assessment towards machine-actionable quality information

open access: yesInternational Journal of Digital Earth
FAIR Principles are a set of high-level guidelines for sharing digital resources. The growing global adoption of the FAIR Principles by policymakers, funders, and organizations compels data professionals, projects, and repositories to demonstrate the ...
Ge Peng   +11 more
doaj   +1 more source

From Conceptualization to Implementation: FAIR Assessment of Research Data Objects

open access: yesData Science Journal, 2021
Funders and policy makers have strongly recommended the uptake of the FAIR principles in scientific data management. Several initiatives are working on the implementation of the principles and standardized applications to systematically evaluate data ...
Anusuriya Devaraju   +9 more
doaj   +1 more source

FAIR Principles and Zenodo

open access: yes, 2023
Presentation about FAIR principles and Zenodo.
Kirwan, Luke, Hackstock, Philip
openaire   +1 more source

AI Fairness: from Principles to Practice

open access: yes, 2022
21 pages, 5 ...
Bateni, Arash   +2 more
openaire   +3 more sources

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

How FAIR can you get? Image Retrieval as a Use Case to calculate FAIR Metrics

open access: yes, 2018
A large number of services for research data management strive to adhere to the FAIR guiding principles for scientific data management and stewardship. To evaluate these services and to indicate possible improvements, use-case-centric metrics are needed ...
Kranzlmüller, Dieter, Weber, Tobias
core   +1 more source

Building a lightweight dataset catalog in Digital Commons 

open access: yesJournal of eScience Librarianship
Introduction: Many academic libraries compile dataset catalogs to make the research data produced by their institutions more findable, accessible, interoperable, and reusable (FAIR).
Amy Reese, Claire Warner, Marla Hertz
doaj   +2 more sources

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