Results 101 to 110 of about 18,679 (292)
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Faithful representations of SL2 over truncated Witt vectors [PDF]
, 2003 Let Γ2 be the six-dimensional linear algebraic k-group SL2(W2), where W2 is the ring of Witt vectors of length two over the algebraically closed field k of characteristic p>2.
McNinch, George J.
core +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Semi-Honest 2-Party Faithful Truncation from Two-Bit Extraction [PDF]
, 2023 As a fundamental operation in fixed-point arithmetic, truncation can bring the product of two fixed-point integers back to the fixed-point representation.
Rui Zhang, Yuting Xiao, Huan Zou
core
THE LEFT REGULAR REPRESENTATION OF A COMMUTATIVE SEPARATIVE SEMIGROUP [PDF]
Journal of Sciences, Islamic Republic of Iran, 1992 In this paper, a commutative semigroup will be written as a disjoint union of its cancellative subsemigroups. Based on this fact we will define the left regular representation of a commutative separative semigroup and show that this representation is ...
doaj
On AdS4 superspace and supergravity
Journal of High Energy PhysicsIn the N = 1 superspace, AdS4 supersymmetry is realized as the non-linear super coordinate transformations. The fermionic coordinates form a faithful non-linear representation of supersymmetry on their own.
Chen-Xu Han, Zhao-Long Wang, Yi Yan
doaj +1 more source
International Journal of Financial StudiesThe informational efficiency of stock prices is conditioned by the level of quality of financial reports, contributing to an accurate assessment of the company’s future performance. By approaching informational quality from two perspectives, we conducted
Daniela Mogîldea, Mihai Carp
doaj +1 more source
Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
On faithful irreducible projective representations of finite groups over a field of characteristic p [PDF]
, 2009 Let K be a field of finite characteristic p and G a finite group with a normal Sylow p-subgroup. We give necessary and sufficient conditions for G to have a faithful irreducible projective representation over K.
Barannyk, Leonid F.
core +1 more source