Results 121 to 130 of about 251,092 (316)
Molecular Oncology, EarlyView.A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath +13 more
wiley +1 more source
YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma
Molecular Oncology, EarlyView.The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy +9 more
wiley +1 more source
Gadamer’s Play as a Criterion for Musical Representation
Critical HermeneuticsThis article explores Gadamer's notion of play as a hermeneutic criterion for understanding subjectivity in musical practice. Based on a distinction between three modes of representation of the work – faithful performance, version, and interpretation ...
Mario Blanco-Tascón
doaj +1 more source
Molecular Oncology, EarlyView.In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern +7 more
wiley +1 more source
The Perception of Discretionary Accounting Regulations on Asset Write-offs
Prace Naukowe Uniwersytetu Ekonomicznego we Wrocławiu, 2019 Flexibility of accounting norms (in the scope of asset write-offs) was introduced in order to enable entities to apply solutions adjusted to their specific character, creating+-* the possibility to use discrete decision-making in a way that undermines ...
Ewa Wanda Maruszewska
doaj
Methods and ProtocolsThe past several decades have borne witness to several breakthroughs and paradigm shifts within the field of cardiovascular medicine, but one component that has remained constant throughout this time is the need for accurate animal models for the ...
Christopher R. Stone +8 more
doaj +1 more source
Algebras with unique minimal faithful representations
Duke Mathematical Journal, 1958 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire +3 more sources
Molecular Oncology, EarlyView.This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert +13 more
wiley +1 more source
Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine
Molecular Oncology, EarlyView.The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu +18 more
wiley +1 more source
On the minimal dimension of a faithful linear representation of a finite\n group [PDF]
, 2021 Alexander Moretó
openalex +1 more source