Results 81 to 90 of about 251,092 (316)
Integration of circadian and hypoxia signaling via non‐canonical heterodimerization
FEBS Letters, EarlyView.CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley +1 more source
FEBS Letters, EarlyView.Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Symmetry, Integrability and Geometry: Methods and Applications, 2007 Zhedanov's algebra AW(3) is considered with explicit structure constants such that, in the basic representation, the first generator becomes the second order q-difference operator for the Askey-Wilson polynomials. It is proved that this representation is
Tom H. Koornwinder
doaj
Parameter Efficient Audio Captioning With Faithful Guidance Using Audio-text Shared Latent Representation [PDF]
, 2023 Arvind Krishna Sridhar +3 more
openalex +1 more source
Constructing faithful matrix representations of Lie algebras
Proceedings of the 1997 international symposium on Symbolic and algebraic computation - ISSAC '97, 1997 By Ados theorem every nite dimensional Lie algebra over a eld of characteristic zero has a faithful nite dimensional representation We consider the algorithmic problem of constructing such a representation for Lie algebras given by a multiplication table An eective version of Ados theorem is proved.
openaire +3 more sources
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
THE LEFT REGULAR REPRESENTATION OF A COMMUTATIVE SEPARATIVE SEMIGROUP [PDF]
Journal of Sciences, Islamic Republic of Iran, 1992 In this paper, a commutative semigroup will be written as a disjoint union of its cancellative subsemigroups. Based on this fact we will define the left regular representation of a commutative separative semigroup and show that this representation is ...
doaj
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source