Results 191 to 200 of about 219,223 (326)

Synergistic Interactions of 5-Fluorouracil with Inhibitors of Protein Kinase CK2 Correlate with p38 MAPK Activation and FAK Inhibition in the Triple-Negative Breast Cancer Cell Line [PDF]

, 2020
Patrycja Wińska, Olena Karatsai, Monika Staniszewska, Mirosława Koronkiewicz, Konrad Chojnacki, Maria Jolanta Rędowicz   +5 more
openalex   +1 more source

Resistance training tempo selectively modulates corticospinal and reticulospinal excitability in humans

The Journal of Physiology, EarlyView.
Abstract figure legend Three weeks of unilateral resistance training (RT) performed under metronome‐paced (MP‐RT) or self‐paced (SP‐RT) conditions increased strength (maximum voluntary force (MVF) and one‐repetition maximum (1RM)) but were accompanied by distinct neural adaptations.
Yonas Akalu, Jamie Tallent, Ashlyn K. Frazer, Ummatul Siddique, Mohamad Rostami, Glyn Howatson, Simon Walker, Dawson J. Kidgell   +7 more
wiley   +1 more source

Strategic selection of MDM2 inhibitors enhances the efficacy of FAK inhibition in mesothelioma based on TP53 genotype. [PDF]

PLoS One
Ning X, Nguyễn TTT, Morinaga T, Tada Y, Shimada H, Hiroshima K, Yamaguchi N, Tagawa M.   +7 more
europepmc   +1 more source

Soft 3D fibrin matrices downregulate FAK expression to promote self-renewal of tumor-repopulating cells [PDF]

Tumor-repopulating cells are a highly tumorigenic subpopulation of cancer cells that exhibit stem cell-like properties (e.g. self-renewal). Previous reports have shown that soft 3D fibrin matrices promote self-renewal in TRCs by promoting histone 3 ...
Wood, Adam Richard
core  

Reviewer #3 (Public Review): FAK loss reduces BRAFV600E-induced ERK phosphorylation to promote intestinal stemness and cecal tumor formation

openalex   +1 more source

The Homeobox Genes: Classification, Regulation, Biological Functions, and Diseases

MedComm, Volume 7, Issue 4, April 2026.
Overview of the homeobox gene superfamily and its pathophysiological roles. The homeobox superfamily comprises several major classes, including ANTP, PRD, TALE, LIM, POU, and others. Among these, the HOX clusters (A–D) play critical roles in embryonic development specifically in conferring cellular identity, regulating morphogenesis, and guiding axial ...
Maedeh Dadzadi, Shahin Ramazi, Mona Darvazi, Sepideh Yoosefi, Melika Abbasi, Shirin Farsad   +5 more
wiley   +1 more source

Window of opportunity study measuring defactinib and avutometinib delivery in glioblastomas. [PDF]

Cancer Chemother Pharmacol
Del Valle MM, Colon EM, Kettimuthu K, Maner-Smith K, Olson JJ, Kucheryavykh LY.   +5 more
europepmc   +1 more source

Overexpression of CEACAM6 activates Src-FAK signaling and inhibits anoikis, through homophilic interactions in lung adenocarcinomas

, 2022
Eun Young Kim, Yoon Jin, Sukin Jeong, Yoon Soo Chang   +3 more
openalex   +1 more source

AI‐assisted design of a VEGFR2 agonistic peptide that promotes angiogenesis and wound repair

Protein Science, Volume 35, Issue 4, April 2026.
Abstract Vascular endothelial growth factor (VEGF) serves as a principal regulator of neovascularization and is essential for vascular regeneration. In this study, we identified and evaluated VEGF Mimetic Peptide3 (VMP3), a novel synthetic peptide developed as a potential VEGFR‐2/VEGF‐A modulator.
Farzana Yasmeen, Rajath Ramachandran, Rameez Hassan Pirzada, Bogeum Choi, Hana Seo, Wook Kim, Moon Suk Kim, Sangdun Choi   +7 more
wiley   +1 more source

FAK signaling pathways are modulated by HSPB8 and BAG3 in breast cancer. [PDF]

Cell Commun Signal
Piccolella M, Tedesco B, Ferrari V, Filippone MG, Tucci FA, Pandolfi A, Casarotto E, Cozzi M, Chierichetti M, Pramaggiore P, Cornaggia L, Milioto C, Magdalena R, Mohamed A, Brodnanova M, Koshal P, Rusmini P, Galbiati M, Tosoni D, Pece S, Cristofani R, Crippa V, Poletti A.   +22 more
europepmc   +1 more source