Results 41 to 50 of about 6,593,005 (300)

Theories of the End of the Novel

Selçuk Üniversitesi Edebiyat Fakültesi Dergisi, 2018
Compared to the other literary genres, the novel is the most recent form that emerged, for example, in English Literature with the rise of the bourgeoisie in the late eighteenth century. It was the work of Defoe, Richardson and Fielding in England in the
Barış Mete
doaj   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Activity report: Monitoring Outcome of Climate-Smart Agriculture in Kaffrine ClimateSmart Village, Senegal [PDF]

, 2020
A Climate-Smart Village (CSV) monitoring survey was carried out in Senegal from 14 to 24 November, 2019 by CCAFS WA and CCAFS/CIAT team. Prior to the survey, a one-week training workshop was organized in Kaffrine, from 8 to 13 November 2019 to build the ...
Adeyemi Chabi, Mamadou Fall, Ouédraogo, Mathieu   +2 more
core  

Falls and Fall Prevention

MedEdPORTAL, 2014
Abstract This workshop is intended to promote and enhance active learning and problem-solving among third-year medical students. At our institution, we decided to transform the existing didactic and case-based falls/fall-prevention workshop into a team-based learning (TBL) format, integrating two minimum geriatric competencies and the latest evidence ...
openaire   +2 more sources

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

Molecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger   +3 more
wiley   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

La percepción de la realidad internacional en el joven Ortega (1883-1907)

Espacio, Tiempo y Forma. Serie V, Historia Contemporánea, 2004
José Ortega y Gasset es el filósofo español más importante del siglo XX. Su pensamiento internacional ha sido poco estudiado. Este trabajo lo aborda en la primera etapa de su vida, hasta 1907 en que concluye su formación.
Juan Pablo Camazón Linacero
doaj   +1 more source

Analyzing Cloud Optical Properties Using Sky Cameras

, 2017
Clouds play a significant role in the fluctuation of solar radiation received by the earth's surface. It is important to study the various cloud properties, as it impacts the total solar irradiance falling on the earth's surface.
Dev, Soumyabrata, Lee, Yee Hui, Manandhar, Shilpa, Meng, Yu Song   +3 more
core   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source