Results 41 to 50 of about 1,204,360 (317)
Vitamin K and age-related diseases
Российский журнал гериатрической медицины, 2023 Vitamin K is a fat-soluble vitamin and its role in metabolism, bone and connective tissue, and blood coagulation is well known. The purpose of this review is to identify and detail the involvement of two vitamin K vitamers, K1 or phylloquinone, and ...
K. A. Eruslanova +3 more
doaj +1 more source
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Sensor-based Fog-Cloud Integrated Human Fall Detection System using Regression-based Gait Pattern Recognition [PDF]
, 2023 G. Rajkumar, Y. Bevish Jinila
openalex +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Theories of the End of the Novel
Selçuk Üniversitesi Edebiyat Fakültesi Dergisi, 2018 Compared to the other literary genres, the novel is the most recent form that emerged, for example, in English Literature with the rise of the bourgeoisie in the late eighteenth century. It was the work of Defoe, Richardson and Fielding in England in the
Barış Mete
doaj +1 more source
Symptoms of Anxiety and Depression Predicting Fall-Related Outcomes Among Older Americans: A Longitudinal Study [PDF]
, 2022 Yuqian Luo +5 more
openalex +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
MedEdPORTAL, 2014 Abstract This workshop is intended to promote and enhance active learning and problem-solving among third-year medical students. At our institution, we decided to transform the existing didactic and case-based falls/fall-prevention workshop into a team-based learning (TBL) format, integrating two minimum geriatric competencies and the latest evidence ...
openaire +2 more sources
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source