Results 51 to 60 of about 16,415 (206)

Payload‐Based Clinical Pharmacology Review of Approved Antibody–Drug Conjugates: Commonalities and Considerations for Streamlined Development

Clinical Pharmacology &Therapeutics, EarlyView.
Antibody–drug conjugates (ADCs) combine the specificity of an antibody with the potency of a cytotoxic drug. Thirteen ADCs, utilizing seven unique cytotoxic payloads and targeting 11 distinct antigens, are currently approved by the US Food and Drug Administration as of June 2025, representing a rapidly growing and highly promising class of anticancer ...
Sijie Lu, Qingqing Xiao, Lixuan Qian, Siyuan Sun, Zhu Zhou, Michael Z. Liao, Chunze Li   +6 more
wiley   +1 more source

Tumor Infiltrating Lymphocyte Therapy Combined With PD‐1/LAG‐3 Inhibition in Patients With Recurrent Platinum‐Resistant Ovarian Cancer

International Journal of Cancer, EarlyView.
The detection of tumor‐infiltrating lymphocytes (TILs) is a positive prognostic factor in ovarian cancer. Moreover, TILs are significantly boosted by immunotherapy, though ovarian cancer patients have seen limited benefit from immune therapies. This study investigated the safety and feasibility of TIL therapy combined with PD‐1 and LAG‐3 inhibitors in ...
Tine J. Monberg, Cathrine L. Lorentzen, Marie C. W. Westergaard, Trine Z. Iversen, Troels H. Borch, Marco Donia, Sigrid M. Mannering, Stine E. W. Banke, Özcan Met, Inge Marie Svane   +9 more
wiley   +1 more source

Paraneoplastic cerebellar degeneration in a patient with a primary fallopian tube adenocarcinoma. A case report and brief review

Gynecologic Oncology Reports, 2017
We describe a 65-year-old woman with subacute cerebellar syndrome expressed as severe ataxia, and the presence of anti Purkinje cell antibodies (Anti-Yo).
Mario Campero, Alberto E. Selman
doaj   +1 more source

Platelet-Derived Growth Factor in the Ovarian Follicle Attracts the Stromal Cells of the Fallopian Tube Fimbriae. [PDF]

PLoS ONE, 2016
During human ovulation, the fallopian tube fimbriae must move to the ovulation site to catch the oocyte. As the tissue-of-origin of the majority of ovarian high-grade serous carcinoma (HGSC), the fallopian tube fimbriae carrying a precursor cancer lesion
Ching-Hua Yeh, Pao-Chu Chen, Chiu-Hua Chen, Che-Fang Hsu, Rui-Len Huang, Dah-Ching Ding, Tang-Yuan Chu   +6 more
doaj   +1 more source

The 9th Edition of the UICC TNM Classification of Malignant Tumours: Updates and Rationale for Change

International Journal of Cancer, EarlyView.
ABSTRACT The standard for assessing and recording the extent of the tumour, a necessity for most malignancies, is the Tumour Node Metastases (TNM) classification. The Union for International Cancer Control (UICC) TNM committee has defined this since the early 1950s.
James D. Brierley, Liesbet J. Van Eycken, Meredith E. Giuliani, Brian A. Rous, Shao Hui Huang, Hisao Asamura, Mary K. Gospodarowicz, Anne W. Lee, Brian O'Sullivan   +8 more
wiley   +1 more source

Clinical and pathological prognostic analysis of 62 patients with fallopian tube carcinoma

Zhongguo aizheng zazhi, 2017
Background and purpose: Fallopian tube carcinoma is a rare malignant tumor of gynecology with a poor prognosis. In this paper, the clinical and pathological factors affecting the prognosis of fallopian tube carcinoma were analyzed retrospectively ...
黄建琴, 肖银平, 朱芝玲
doaj  

Primary Squamous Cell Carcinoma of the Fallopian Tube- Report of a Case and Short Review of Primary Malignancies of the Fallopian Tube

, 2007
Primary squamous cell carcinoma of the fallopian tube is the rarest of all the gynecological malignancies, which is often diagnosed as a benign entity or as ovarian pathology. We present the fourth case of primary squamous cell carcinoma of the fallopian
Sarma, N H, Srivastava, R
core   +1 more source

Ovarian Cancer: Epidemiology, Disease Mechanisms, New Diagnosis and Treatment Strategies, and Research Directions

iNew Medicine, EarlyView.
ABSTRACT Ovarian cancer (OC) continues to be the deadliest gynecological malignancy and a significant cause of cancer‐related mortality among women worldwide. Standard treatment strategies typically entail platinum‐based chemotherapy in conjunction with cytoreductive surgery.
Zunera Khalid, Weirong Fan, Farah Nazir, Yixiang Xing, Tengchuan Jin   +4 more
wiley   +1 more source

Primary fallopian tube carcinoma: Preoperative diagnostic dilemma

, 2023
Primary fallopian tube carcinoma is an uncommon female genital tract malignancy that resembles epithelial ovarian neoplasm clinically and radiologically.
Shalini Rawat, Shalini Bhalla, Sameer Gupta   +2 more
core   +1 more source

Primary Carcinoma of the Fallopian Tube [PDF]

The American Journal of the Medical Sciences, 1898
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openaire   +2 more sources