Results 101 to 110 of about 14,852 (255)
This review systematically deconstructs the pathological efferocytic—metabolic axis in tumours, framing it as a three‐stage, self‐reinforcing cycle: from metabolite‐driven macrophage recruitment, through hijacked surface recognition, to post‐phagocytic metabolic reprogramming that locks in immunosuppression.
Qianlu Yang, Jie Yan, Qianxi Yang
wiley +1 more source
ABSTRACT The endometrium, the mucosal lining of the uterus, is a highly regenerative tissue that undergoes cyclic remodeling guided by tightly regulated levels of estrogen and progesterone. Stromal cells, including fibroblasts, are embedded within the connective tissue of the endometrium and contribute to the rapidly changing extracellular matrix (ECM).
Grace K. Hinds +5 more
wiley +1 more source
Female infertility remains one of the important problems of modern gynecology. The most common form of female infertility is tubal-peritoneal, which develops as a result of inflammatory diseases of the uterine appendages or surgical interventions on the ...
Сергей Валериевич Рыбников +5 more
doaj
Detection of serous precursor lesions in resected fallopian tubes from patients with benign diseases and a relatively low risk for ovarian cancer [PDF]
Naoyo Nishida +2 more
openalex +1 more source
Neurons, immune cells, and other cellular components within the disease microenvironment (such as stromal cells and tumor cells) constitute a dynamically evolving ecosystem. Neurons directly modulate immune cell activity and inflammatory responses through the release of neurotransmitters (e.g., norepinephrine and CGRP), while also promoting tumor ...
Xin Guo +11 more
wiley +1 more source
Beyond olfaction: New insights into human odorant binding proteins
Abstract Until today, the exact function of mammalian odorant binding proteins (OBPs) remains a topic of debate. Although their main established function lacks direct evidence in human olfaction, OBPs are traditionally believed to act as odorant transporters in the olfactory sense. Now, available RNA‐seq and proteomics data identified the expression of
Mifen Chen +5 more
wiley +1 more source
Background While papillary cystadenomas of the epididymis are relatively common, the occurrence of papillary cystadenomas in female individuals, particularly in the ovaries, remains exceedingly rare.
Haifa Bergaoui +10 more
doaj +1 more source
Therapeutic targeting of chromatin alterations in leukemia and solid tumors
Abstract Alterations in chromatin conformation and post‐translational modification of histones have become increasingly recognized as critical drivers of cancer development, progression, and therapy resistance. Recent advances in drug development have led to the establishment of several highly selective small molecule inhibitors, several of which are ...
Florian Perner +7 more
wiley +1 more source
ABSTRACT Chronic pain significantly impacts many individuals with endometriosis, yet cognitive biases—specifically interpretation bias (IB) and memory recall bias (MRB)—remain underexplored in this context. This study examined IB and MRB in individuals with endometriosis compared with pain‐free controls and explored their associations with pain ...
Sophia Nematollahi +2 more
wiley +1 more source
TDP‐43 hyperphosphorylation occurs in neurodegenerative diseases, however, it is not a driver of TDP‐43 aggregation, but enhances TDP‐43 solubility, suggesting that TDP‐43 hyperphosphorylation is protective. Toxicity may arise from a broader phosphorylation‐driven cellular pathway disruption.
Simone Mosna, Dorothee Dormann
wiley +1 more source

