Results 101 to 110 of about 14,537 (220)
Cancer, Volume 132, Issue S1, 1 June 2026.Abstract Antibody–drug conjugates (ADCs) represent a major advance in precision oncology, combining the selectivity of monoclonal antibodies with the cytotoxic potency of chemotherapy. By enabling targeted intracellular delivery of highly potent payloads, ADCs aim to maximize antitumor activity while minimizing systemic toxicity. This review summarizes
André Mansinho +3 more
wiley +1 more source
Health Science Reports, Volume 9, Issue 6, June 2026.ABSTRACT Background and Aim Intestinal flora composition in polycystic ovary syndrome (PCOS) varies, and the relationship between intestinal flora, fecal metabolites, clinical characteristics, and PCOS pathogenesis remains unclear. This study aimed to elucidate the gut microbiota characteristics of patients with PCOS, focusing on changes in normal ...
Yu‐Mei Li +4 more
wiley +1 more source
Serous tubal intraepithelial lesion (STIL) is a rare benign lesion of the fallopian tube epithelium characterized by atypical epithelial cells with morphological anomalies, marked by the accumulation of p53 protein and normal or slightly increased ...
Tretjakova, Ksenija +1 more
core +1 more source
International Journal of Gynecology &Obstetrics, Volume 173, Issue 3, Page 1334-1342, June 2026.Abstract Objective In the dose‐escalation part of Study 101, which included multiple tumor types, objective responses were observed in 10 of 22 patients across multiple dose levels of farletuzumab ecteribulin (FZEC). We explored the safety/antitumor activity of FZEC in patients with platinum‐resistant ovarian cancer (PROC) from the Study 101 expansion ...
Kan Yonemori +11 more
wiley +1 more source
Journal of Clinical Ultrasound, Volume 54, Issue 5, Page 1113-1121, June 2026.In this study, 3D‐TVS measurements of the uterine junction zone (JZ) in 120 patients showed that a JZmax threshold of ≥ 0.45 cm yielded 77% sensitivity and 89% specificity for adenomyosis diagnosis. Notably, JZ thickness varies minimally with age, demonstrating its stability and excellent diagnostic performance.
Mengyu Li +3 more
wiley +1 more source
Organoids: From Bench to Bedside Applications
MedComm, Volume 7, Issue 6, June 2026.Organoids, as a groundbreaking biomedical research platform, utilize adult stem cells (ASCs), embryonic stem cells (ESCs), and induced pluripotent stem cells (iPSCs) as sources. By integrating specific growth and differentiation signals within an extracellular matrix (e.g., Matrigel), organoids guide cells to self‐assemble into three‐dimensional ...
Kelin Li +6 more
wiley +1 more source
Abstract 5480: Expression and function of EVI1 and EVI1s (Δ324) ovarian cancer
, 2010 Objective: The MDS1 and EVI1 complex locus (MECOM) located at the 3q26 locus is amplified in many cancers and gives rise to a number of alternatively spliced transcripts and proteins including EVI1 and MDS1-EVI1 (ME).
Susan Dalton +5 more
core +1 more source
Redox Regulation and Oxidative Stress in Health and Disease: Mechanisms and Therapeutic Targeting
MedComm – Future Medicine, Volume 5, Issue 2, June 2026.Reactive species serve crucial roles which are tightly regulated in both physiological as well as disease states. At physiological levels, these species are integral to redox signaling, while uncontrolled redox promotes disease pathology. This review examines the dysregulation of these processes.
Mohammad Hossein Azadi +2 more
wiley +1 more source