Results 81 to 90 of about 32,735 (200)

Organoid Models to Study Human Infectious Diseases

Cell Proliferation, EarlyView.
Our manuscript reviews the role of organoids as models for studying human infectious diseases, highlighting their irreplaceable contributions to drug testing and vaccine development for significant infectious diseases including HIV, ZIKV, SARS‐CoV‐2 and MPXV.
Sijing Zhu, Dan Chen, Xinzhi Yang, Liuliu Yang, Yuling Han   +4 more
wiley   +1 more source

Analysis of benign neoplasms of the rete testis formerly termed “Sertoliform cystadenomas” demonstrates that they are not Sertoli cell tumours with intra‐rete growth

Histopathology, EarlyView.
Benign tumours of the rete testis are uncommon and include mostly cystadenomas and adenomas, including a subset with tubular or tubulopapillary architecture. The latter show morphological similarities with Sertoli cell tumours and were previously termed Sertoliform cystadenomas of the rete testis.
Katrina Collins, Kvetoslava Michalova, Dario de Biase, Costantino Ricci, Giovanni Tallini, Jennifer B Gordetsky, Muhammad T Idrees, Maurizio Colecchia, Thomas M Ulbright, Andres M Acosta   +9 more
wiley   +1 more source

Clinical Factors Affecting the Quality of Life of Women With Endometriosis

Journal of Advanced Nursing, EarlyView.
ABSTRACT Aim The study aimed to analyse selected clinical data affecting the quality of life of women with endometriosis. Design A cross‐sectional study. Method The study was conducted in 2020–2022 among 425 women with endometriosis receiving health care. A diagnostic survey method with a questionnaire technique was used.
Agnieszka Bień, Aleksandra Pokropska, Joanna Grzesik‐Gąsior, Magdalena Korżyńska‐Piętas, Marta Zarajczyk, Ewa Rzońca, Krzysztof Jurek   +6 more
wiley   +1 more source

Clinical value of amylase and its prognostic accuracy in guinea pigs (Cavia porcellus)

Journal of Small Animal Practice, EarlyView.
Objectives To retrospectively evaluate plasma amylase concentrations in client‐owned guinea pigs (Cavia porcellus) and determine a possible association with mortality. Materials and Methods Medical records of guinea pigs that had a biochemistry panel from four institutions were retrospectively reviewed.
A. R. Souza, S. M. Ozawa, M. J. Sadar, M. D. Gleeson, R. James, S. Chen, N. Di Girolamo   +6 more
wiley   +1 more source

Living with acuteness in chronic illness: The temporal underpinnings of endometriosis

Medical Anthropology Quarterly, EarlyView.
Abstract This article explores how acuteness is experienced by people with endometriosis in Finland. Drawing on in‐depth interviews as well as anonymous written endometriosis stories, we trace instances when the sense of chronicity and cyclicality of endometriosis is disrupted by a possibility of risk to life. These instances include when endometriosis
Venla Oikkonen, Elina Helosvuori
wiley   +1 more source

Identification of potential cell surface targets in patient‐derived cultures toward photoimmunotherapy of high‐grade serous ovarian cancer

Photochemistry and Photobiology, EarlyView.
Through mRNA sequencing, proteomics, and flow cytometry, we identified potential cell surface targets toward tumor‐targeted, activatable photoimmunotherapy (taPIT) in advanced high‐grade serous ovarian cancers (HGSOCs) with low EGFR expression. The reliance on EGFR overexpression has been a major limitation of taPIT, which this study seeks to address ...
Sudip Timilsina, Anish Raju Amara, Rafay Abu, Bryan Q. Spring   +3 more
wiley   +1 more source

Transforming treatment paradigms: Focus on personalized medicine for high‐grade serous ovarian cancer

CA: A Cancer Journal for Clinicians, EarlyView.
Abstract High‐grade serous ovarian cancer (HGSOC) is the most common and aggressive subtype of ovarian cancer, accounting for approximately 70% of all ovarian cancer cases and contributing significantly to the high mortality rates associated with this disease.
Pawel Kordowitzki, Britta Lange, Kevin M. Elias, Marcia C. Haigis, Sylvia Mechsner, Ioana Elena Braicu, Jalid Sehouli   +6 more
wiley   +1 more source

Transcription factor GTF2I regulates osteoclast differentiation through mediating miR‐134‐5p and MAT2A expressions

Journal of Cell Communication and Signaling, Volume 19, Issue 2, June 2025.
Abstract This study explored the possible effect of transcription factor GTF2I on the differentiation of osteoclasts and its regulation on the miR‐134‐5p/MAT2A axis. RANKL‐induced osteoclasts were measured for expressions of GTF2I, miR‐134‐5p, and MAT2A. The number and size of osteoclasts were assessed after TRAP staining. The expressions of osteoclast
Lian Tang, Yanshi Liu, Jiyuan Yan, Lin Yuan, Zhaojun Wang, Zhong Li   +5 more
wiley   +1 more source

Prognostic values of molecular subtypes and SWI/SNF protein expression in de‐differentiated/undifferentiated endometrial carcinoma

Histopathology, Volume 86, Issue 7, Page 1053-1063, June 2025.
Our study characterised the molecular subtypes and SWI/SNF protein expression in de‐differentiated/undifferentiated endometrial carcinoma (DD/UDEC) assembled at one single institution. We demonstrated that while MMR, p53 and SWItch/sucrose non‐fermentable (SWI/SNF) protein expression status did not provide prognostic value, all molecular subtypes of DD/
Chae Young Shin, Bengul Gokbayrak, Valerie L Tao, Noorah Almadani, Eunice S Li, Rebecca Ho, Felix KF Kommoss, Jutta Huvila, Derek Chiu, Samuel Leung, Basile Tessier‐Cloutier, David G Huntsman, C Blake Gilks, Jessica N McAlpine, Lynn Hoang, Yemin Wang   +15 more
wiley   +1 more source

Cytologic Histotyping of Gynecologic Malignancies in Peritoneal Fluids Is Reliable When Compared to Its Corresponding Surgical Specimen

Diagnostic Cytopathology, Volume 53, Issue 5, Page 215-226, May 2025.
ABSTRACT Background Cytologic examination of peritoneal fluid (PTFL) often represents the first and only pathologic specimen available to guide management of gynecologic malignancies (GMs). This study examines the cytohistologic correlation between histotyping of GM in PTFL and its corresponding surgical specimen (SS). Methods The study retrospectively
Thomas Sabljic, Si Kei (Sandy) Lou
wiley   +1 more source