Results 41 to 50 of about 5,583,624 (329)

False negative result of polymerase chain reaction in very early stages of acute retinal necrosis

Journal of Ophthalmic Inflammation and Infection, 2023
Abstract Background Viral nucleic acid testing of intraocular fluid using polymerase chain reaction (PCR) is a major laboratory examination in the diagnosis of acute retinal necrosis (ARN). Importantly, false negative PCR results may occur in several special situations.
Haibo Wang, Zhuyun Qian, Lin Cui, Beichen Liu, Jixin Zou, Lu Wang, Yong Tao, Lijun Zhang, Lei Jin   +8 more
openaire   +3 more sources

Perfectionism and competitive anxiety in athletes: Differentiating striving for perfection and negative reactions to imperfection [PDF]

, 2007
Whereas some researchers have argued that perfectionism in sports is maladaptive because it is related to dysfunctional characteristics Such as higher competitive anxiety, the present article argues that striving for perfection is not maladaptive and is ...
Stoeber, Joachim, Stoll, Oliver, Otto, Kathleen, Pescheck, Eva, Becker, Claudia   +4 more
core   +1 more source

Validation of a Commercial Glanders ELISA as an Alternative to the CFT in International Trade of Equidae

Frontiers in Veterinary Science, 2021
Glanders, caused by Burkholderia (B.) mallei is a notifiable zoonotic disease in equidae. For international trade and movement of equids, certificates of negative serological test results for antibodies against B. mallei are required.
Mandy Carolina Elschner, Falk Melzer, Harisankar Singha, Saqib Muhammad, Ian Gardner, Heinrich Neubauer   +5 more
doaj   +1 more source

Extensive transmission of Mycobacterium tuberculosis from 9 year old child with pulmonary tuberculosis and negative sputum smear [PDF]

, 2008
Patients with pulmonary tuberculosis and either a positive sputum smear or cavitating pulmonary lesions have been considered to be infectious1 as these indicate higher bacterial load accumulating with longer duration of infection. The source of infection
Howard, J., Chalkley, D, McEvoy, M., Paranjothy, S, Bracebridge, S, Paranjothy, S., Lack, K., Eisenhut, M, Abubakar, I, Chalkley, D., Thomas, S., McEvoy, M, Eisenhut, M., Lilley, M., Howard, J, Paranjothy, Shantini, Thomas, S, Lilley, M, Mulla, R, Abubakar, I., Bracebridge, S., Lack, K, Mulla, R.   +22 more
core   +1 more source

Diagnostics of cutaneous adverse drug reactions: evaluation of patch tests, lymphocyte transformation tests, and drug provocation tests

Journal of Cutaneous Immunology and Allergy
BackgroundPatch tests (PT) and/or lymphocyte transformation tests (LTT) are typically performed, when diagnosed with cutaneous adverse drug reactions (CADR). However, their positivity rates can vary depending on the rash type.
Tomomu Ishikawa, Risa Tamagawa-Mineoka, Risa Tamagawa-Mineoka, Koji Masuda, Norito Katoh, Takeshi Fukumoto   +5 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Monoclonal and polyclonal antibodies for ante- and post-mortem detection of PrPSc in sheep

Semina: Ciências Agrárias, 2015
Scrapie is a disease that affects sheep and goats and is characterized by the accumulation of an abnormal isoform (PrPSc) of the cellular prion protein, PrPC, in the central nervous system (CNS) and in lymphoid tissues.
Michele Dietrich Moura Costa , Lorenzo González, Caroline Pinto de Andrade , David Driemeier, Jair Rodini Engracia Filho , Cristina Santos Sotomaior   +5 more
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Fabrication of a Microfluidic Test Device with a 3D Printer and Its Combination with the Loop Mediated Isothermal Amplification Method to Detect Streptococcus pyogenes

Micromachines
New rapid, reliable, and cost-effective alternative systems are needed for the rapid diagnosis of Streptococcus pyogenes. The aim of this study was to fabricate a microfluidic test device to detect Streptococcus pyogenes by combining the Loop-mediated ...
Hayriye Kirkoyun Uysal, Meltem Eryildiz, Mehmet Demirci   +2 more
doaj   +1 more source