Results 91 to 100 of about 1,479,365 (284)

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

Multiple-Target Matching Algorithm for SAR and Visible Light Image Data Captured by Multiple Unmanned Aerial Vehicles

open access: yesDrones
Unmanned aerial vehicle (UAV) technology has witnessed widespread utilization in target surveillance activities. However, cooperative multiple UAVs for the identification of multiple targets poses a significant challenge due to the susceptibility of ...
Hang Zhang, Jiangbin Zheng, Chuang Song
doaj   +1 more source

User acceptance of intelligent avionics: A study of automatic-aided target recognition [PDF]

open access: yes
User acceptance of new support systems typically was evaluated after the systems were specified, designed, and built. The current study attempts to assess user acceptance of an Automatic-Aided Target Recognition (ATR) system using an emulation of such a ...
Becker, Curtis A.   +2 more
core   +1 more source

Indeterministic Handling of Uncertain Decisions in Duplicate Detection [PDF]

open access: yes, 2010
In current research, duplicate detection is usually considered as a deterministic approach in which tuples are either declared as duplicates or not. However, most often it is not completely clear whether two tuples represent the same real-world entity or
Keulen, Maurice van   +2 more
core   +2 more sources

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

A novel bootstrapping method for positive datasets in cascades of boosted ensembles [PDF]

open access: yes, 2010
We present a novel method for efficiently training a face detector using large positive datasets in a cascade of boosted ensembles. We extend the successful Viola-Jones [1] framework which achieved low false acceptance rates through bootstrapping ...
Barczak, A.L.C.   +2 more
core  

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

El paso en falso con respecto al cual no retrocede Heidegger [PDF]

open access: yes, 2009
The aim of this paper is to show the achievements and the limit of Heidegger’s thought from the analysis of the two false steps. The first false step shows us what the target of his philosophical criticism is, whereas the second false step shows us ...
Rojas-Jiménez, A. (Alejandro)
core  

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

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