Results 71 to 80 of about 1,479,365 (284)

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Error-Constrained Entropy-Minimizing Strategies for Multi-UAV Deception Against Networked Radars

Entropy
In complex electromagnetic environments, spatial coupling uncertainties—position errors and timing jitter—increase false target information entropy, reducing strategy effectiveness and posing challenges for robust UAV swarm track deception.
Honghui Ban, Jifei Pan, Zheng Wang, Rui Cui, Yuting Ming, Qiuxi Jiang   +5 more
doaj   +1 more source

Constraining the False Positive Rate for Kepler Planet Candidates with Multi-Color Photometry from the GTC

, 2012
Using the OSIRIS instrument installed on the 10.4-m Gran Telescopio Canarias (GTC) we acquired multi-color transit photometry of four small (Rp < 5 R_Earth) short-period (P < 6 days) planet candidates recently identified by the Kepler space mission ...
Bakos, Bakos, Borucki, Borucki, Claret, Colón, Colón, Désert, Eastman, Eric B. Ford, Knicole D. Colón, Landsman, Lillo-Box, Lissauer, Lissauer, Mandel, Morton, Prša, Robert C. Morehead, Slawson, Stetson   +20 more
core   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Moving Target Detection with Modified Logarithm Background Subtraction and Its Application to the GF-3 Spotlight Mode

Remote Sensing, 2019
Spaceborne spotlight SAR mode has drawn attention due to its high-resolution capability, however, the studies about moving target detection with this mode are less.
Wenjie Shen, Wen Hong, Bing Han, Yanping Wang, Yun Lin   +4 more
doaj   +1 more source

Deception electronic counter‐countermeasure applicable to multiple jammer sources in distributed multiple‐radar system

IET Radar, Sonar & Navigation, 2021
Deception jamming poses a fatal threat to the radar performance, and its jamming performance has been greatly improved through networking. However, available deception electronic counter‐countermeasure (ECCM) methods are mostly developed in the scenario ...
Shanshan Zhao, Ziwei Liu
doaj   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Deception Velocity-Based Method to Discriminate Physical Targets and Active False Targets in a Multistatic Radar System

Remote Sensing
Due to the silent operation of the receiver station in a multistatic radar system, it is difficult for the jammer to generate the cooperative active deception target for the multistatic radar system.
Qiang Li, Yumei Guo, Peng Zhang, Hong Xu, Linrang Zhang, Zhanye Chen, Yan Huang   +6 more
doaj   +1 more source

New matrix constant false alarm rate detectors for radar target detection

The Journal of Engineering, 2019
Matrix constant false alarm rate (M-CFAR) detector based on information geometry provides a novel scheme to the detection of target in sea clutter environment for pulse Doppler radar with small bunch of pulses. The detection performance of the existing M-
Wenjing Zhao, Deyue Zou, Wenlong Liu, Minglu Jin   +3 more
doaj   +1 more source