Results 111 to 120 of about 4,211 (172)

Maternal age effects on myometrial expression of contractile proteins, uterine gene expression, and contractile activity during labor in the rat [PDF]

, 2015
Advanced maternal age of first time pregnant mothers is associated with prolonged and dysfunctional labor and significant risk of emergency cesarean section.
Agarwal, Agostinis, Allen, Andersson, Arai, Arend, Ares, Arrowsmith, Arsenov, Aussel, Babiychuk, Bakircioglu, Bell, Bots, Braciale, Brasier, Brckalo, Brigelius-Flohé, Brown, Bréart, Castrillo, Challis, Chan, Chapple, Chevillard, Cluff, Coutinho, Dong, Doring, Drab, Duffy, Ebisch, Eckstrum, Elce, Elliot, Elmes, Elovitz, Friel, Gardner, Garreau, Gerlo, Gil, Gomez-Lopez, Greenberg, Gross, Grossman, Guihard, Haddad, Hamilton, Hemmerich, Heng, Hung, Joseph, Joseph, Keirse, Kim, King, Klukovits, Kozinszky, Larsen, Ledingham, Lee, Leung, Lopez Bernal, Luke, Luu-The, Ly, Lye, Lye, Main, Malmström, Martin, Matthews, McGinn, McNally, Milligan, Mittal, Montan, Morgan, Morrison, Nie, Noble, Norman, O'Connor, Ogawa, Okamoto, Osman, Paganini, Paik, Park, Payne, Pennefather, Phillips, Quaas, Ramkhelawon, Richeri, Riley, Roberts, Romero, Schellenberg, Schlegel, Schousboe, Schutzer, Scott, Sengupta, Sennstrom, Shaul, Shiratori, Simon, Singh, Smith, Smith, Somara, Stepan, Sugino, Sykes, Tadagavadi, Tato, Telfer, Temma-Asano, Thomson, Toescu, Vassalli, Ventura, Wang, Wathes, Wathes, Willecke, Winkler, Yahata, Yellon, Young, Yuan, Zante, Zhang, Zhao, Zhu, Zoubina, Zuo   +138 more
core   +2 more sources

Increased autophagy in EphrinB2-deficient osteocytes is associated with elevated secondary mineralization and brittle bone [PDF]

, 2019
Mineralized bone forms when collagen-containing osteoid accrues mineral crystals. This is initiated rapidly (primary mineralization), and continues slowly (secondary mineralization) until bone is remodeled. The interconnected osteocyte network within the
Vrahnas, Christina, Blank, Martha, Dite, Toby A, Tatarczuch, Liliana, Ansari, Niloufar, Crimeen-Irwin, Blessing, Nguyen, Huynh, Forwood, Mark R, Hu, Yifang, Ikegame, Mika, Bambery, Keith R, Petibois, Cyril, Mackie, Eleanor J, Tobin, Mark J, Smyth, Gordon K, Oakhill, Jonathan S, Martin, T John, Sims, Natalie A   +17 more
core   +1 more source

Expression Changes of Genes Involved in Autophagy of the Endoplasmic Reticulum Network in Animal Models of Alzheimer’s Disease

Majallah-i dānishgāh-i ̒ulūm-i pizishkī-i Arāk, 2020
Background and Aim: This study aimed to investigate the association between Endoplasmic Reticulum autophagy (ER-phagy) and Alzheimer’s Disease (AD) by analyzing the expression patterns of related genes in animal models.
Zakiyeh Gharib, Naser Sanchooli, Nima Sanadgol   +2 more
doaj  

ER-to-lysosome-associated degradation acts as failsafe mechanism upon ERAD dysfunction

EMBO Reports
The endoplasmic reticulum (ER) produces proteins destined to organelles of the endocytic and secretory pathways, the plasma membrane, and the extracellular space.
Elisa Fasana, Ilaria Fregno, Carmela Galli, Tatiana Soldà, Maurizio Molinari   +4 more
doaj   +1 more source

De novo pathogenic DNM1L variant in a patient diagnosed with atypical hereditary sensory and autonomic neuropathy

Molecular Genetics & Genomic Medicine, 2019
Background Profiling the entire genome at base pair resolution in a single test offers novel insights into disease by means of dissection of genetic contributors to phenotypic features.
Maja Tarailo‐Graovac, Farah R. Zahir, Irena Zivkovic, Michelle Moksa, Kathryn Selby, Sunita Sinha, Corey Nislow, Sylvia G. Stockler‐Ipsiroglu, Ruth Sheffer, Ann Saada‐Reisch, Jan M. Friedman, Clara D. M. vanKarnebeek, Gabriella A. Horvath   +12 more
doaj   +1 more source

CKAP4 in hepatocellular carcinoma: competitive RETREG1/FAM134B binding, reticulophagy regulation, and cancer progression

Autophagy
RETREG1/FAM134B is known for its role as a reticulophagy receptor. Our previous study established that RETREG1 is upregulated in hepatocellular carcinoma (HCC) and contributes to disease progression by activating the AKT signaling pathway. However, the specific mechanisms underlying the elevated expression of RETREG1 in HCC remain unclear.
Jie, Mo, Chen, Su, Pengcheng, Li, Zhenhua, Yang, Ran, Tao, Qiumeng, Liu, Chaoyi, Yuan, Lei, Xu, Qianyun, Ge, Deng, Ning, Huifang, Liang, Haidan, Zhu, Yan, Luo, Xiaoping, Chen, Jin, Chen, Bixiang, Zhang   +15 more
openaire   +2 more sources

高氧诱导大鼠肺泡Ⅱ型细胞内质网自噬与其功能的关系

Zhongguo shiyan zhenduanxue
目的 探讨不同时间高浓度氧对肺泡Ⅱ型细胞（AECII）内质网自噬与肺泡表面活性物质产生功能之间的关系。方法 将大鼠RLE-6TN细胞分为对照组（C组，21%O2常规培养72 h）、高氧H1、H2、H3、H4组（95%O2分别培养12、24、48、72 h）。实时荧光定量PCR法检测内质网自噬受体ATL3、CCPG1、FAM134B、RTN3、SEC62的mRNA水平，Western blot法检测内质网自噬相关蛋白ATL3、CCPG1、FAM134B、RTN3、SEC62的水平 ...
刘嘉璐, 于恺华, 郭鸿, 姚莹, 鲍振星, 施华清, 李玉兰   +6 more
doaj  

Ca+2 and Nε-lysine acetylation regulate the CALR-ATG9A interaction in the lumen of the endoplasmic reticulum

Scientific Reports
The acetylation of autophagy protein 9 A (ATG9A) in the lumen of the endoplasmic reticulum (ER) by ATase1 and ATase2 regulates the induction of reticulophagy.
Megan M. Braun, Brendan K. Sheehan, Samantha L. Shapiro, Yun Ding, C. Dustin Rubinstein, Brent P. Lehman, Luigi Puglielli   +6 more
doaj   +1 more source

AFB1 exposure promotes SIV replication and lung damage via RIG-I- and p38-mediated RETREG1/FAM134B-dependent endoplasmic reticulum autophagy

Ecotoxicology and Environmental Safety
Aflatoxin B1 (AFB1) contamination is common worldwide and highly harmful to humans and animals. Our previous studies suggested that AFB1 exposure promotes the replication of H1N1 swine influenza virus (SIV). However, its mechanism is not clear.
Wenshuo Zhao, Siyao Pang, Jinlong Zhang, Zhaoran Yao, Yuqi Song, Yuhang Sun   +5 more
doaj   +1 more source

Role of FAM134B in liver cancer

, 2013
FAM134B (family with sequence similarity 134, member B) isimli protein laboratuarımızda ilk olarak seviyelerinin artışı hepatosellüler karsinomda hücre yaşlanması, siroz ve mezenkimal benzeri davranış durumları ile bağlantılı olabilecek bir protein olarak dikkat çekti, ve bu tez çalışmasının amacı FAM134B?nin hepatosellüler karsinomdaki rolünü ...
openaire   +2 more sources