PRRSV non-structural protein 5 inhibits antiviral innate immunity by degrading multiple proteins of RLR signaling pathway through FAM134B-mediated ER-phagy. [PDF]
Wang J +9 more
europepmc +1 more source
Degradation of STIM1 through FAM134B-mediated ER-phagy is potentially involved in cell proliferation. [PDF]
Kajiho H, Sakisaka T.
europepmc +1 more source
GSTK1 and RETREG1/FAM134B-mediated reticulophagy attenuates tubular injury in diabetic nephropathy through endoplasmic reticulum stress and apoptosis. [PDF]
Zhang S +14 more
europepmc +1 more source
Autophagy, ER-phagy and ER Dynamics During Cell Differentiation.
Cillo M +3 more
europepmc +1 more source
Reticulophagy receptor FAM134C restrains BMP receptor signaling. [PDF]
Gu S +15 more
europepmc +1 more source
Overexpression of long noncoding RNA DUXAP8 inhibits ER-phagy through activating AKT/mTOR signaling and contributes to preeclampsia. [PDF]
Wei XH +8 more
europepmc +1 more source
Disturbances of endoplasmic reticulum proteostasis in neurodevelopmental disorders. [PDF]
Medinas DB +4 more
europepmc +1 more source
Flavivirus NS2A orchestrates reticulophagy to enhance viral pathogenicity. [PDF]
Zhang L, Qin Y, Chen M.
europepmc +1 more source
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Molecular characterization of wild-type and HSAN2B-linked FAM134B
Molecular Biology Reports, 2023Family with sequence similarity 134, member B (FAM134B), also known as Reticulophagy regulator 1 (RETREG1), is an ER-phagy receptor involved in ER homeostasis. Congenital mutations in the FAM134B gene have been reported to be associated with hereditary sensory and autonomic neuropathy type 2B (HSAN2B); however, the molecular differences between wild ...
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