Results 51 to 60 of about 4,194 (200)

Pharmacokinetics and safety of famciclovir in children with herpes simplex or varicella-zoster virus infection.

open access: yes, 2009
Two multicenter, open-label, single-arm, two-phase studies evaluated single-dose pharmacokinetics and single- and multiple-dose safety of a pediatric oral famciclovir formulation (prodrug of penciclovir) in children aged 1 to 12 years with suspicion or ...
Arguedas, A   +12 more
core   +1 more source

Compost Tea as a Natural Bioactive Solution: Unlocking the Antimicrobial and Antiviral Potential of Bell Pepper and Citrus Wastes

open access: yesEnvironmental Microbiology Reports, Volume 18, Issue 1, February 2026.
Compost teas derived from bell pepper and citrus waste are rich in bioactive phenolics and lignin derivatives, showing strong antibacterial activity against gram‐positive bacteria and potent antiviral effects against HSV‐1 and RSV. These findings highlight their potential as sustainable, circular bioresources for biomedical applications.
Maria Vittoria Verrillo   +7 more
wiley   +1 more source

A phase 2 open-label clinical trial to determine the effect of Famciclovir on Epstein-Barr virus activity as measured by EBV shedding in the saliva of patients with Multiple Sclerosis

open access: yes, 2023
Background: Despite increasing evidence that Epstein–Barr virus (EBV) plays a causal role in MS, no treatments have been shown to reduce EBV turnover.
Dobson, R
core   +1 more source

Pharmacokinetic modeling of penciclovir and BRL42359 in the plasma and tears of healthy cats to optimize dosage recommendations for oral administration of famciclovir. [PDF]

open access: yes, 2016
OBJECTIVES To determine, following oral administration of famciclovir, pharmacokinetic (PK) parameters for 2 of its metabolites (penciclovir and BRL42359) in plasma and tears of healthy cats so that famciclovir dosage recommendations for the treatment of
Thomasy, Sara M   +8 more
core   +1 more source

QUIMIOPROFILAXIA DE HERPES GENITAL

open access: yesRevista da Sociedade Portuguesa de Dermatologia e Venereologia, 2014
O herpes genital é uma das doenças sexualmente transmissíveis mais comuns, com distribuição mundial. Os episódios recorrentes desta doença estão associados a um grau de morbilidade importante pelo que a quimioprofilaxia das recorrências assume um papel ...
Ana Isabel Teixeira   +2 more
doaj   +1 more source

Characteristics of Acyclovir‐Resistant Herpes Simplex Virus Infection in Hematological Patients

open access: yesJournal of Oral Pathology &Medicine, Volume 55, Issue 2, Page 244-248, February 2026.
ABSTRACT Objective Acyclovir‐resistant herpes simplex virus infections pose a significant challenge in immunosuppressed patients. This study aimed to characterize the clinical features, treatment outcomes, and mortality associated with acyclovir‐resistant herpes simplex virus infection. Materials and Methods A retrospective analysis was conducted on 18
Reema Shehadeh   +7 more
wiley   +1 more source

Bee products as alternatives in the treatment of viral infections

open access: yesJournal of the Science of Food and Agriculture, Volume 106, Issue 1, Page 33-54, 15 January 2026.
Abstract Medicines used in the treatment of viral infections usually reduce symptoms. There is a need to develop drugs that inhibit the viruses and do not merely relieve the symptoms. Natural bee products possess many pharmacological properties and are widely used in folk medicine. There are many studies on the antibacterial effects of bee products but
Michał Otręba   +3 more
wiley   +1 more source

Exploring the Antiviral Potential of Tungsten Oxide Nanoparticles Against Herpes Simplex Virus Type 1: A Promising Alternative to Acyclovir

open access: yesIET Nanobiotechnology, Volume 2026, Issue 1, 2026.
Herpes simplex virus type 1 (HSV‐1) is responsible for the majority of cold sores, herpetic keratitis‐induced blindness, profound skin lesions, and encephalitis that can be fatal. Currently, acyclovir and its derivatives are the first‐line therapy for the treatment of HSV‐1 infection.
Abdulhussain Kadhim Jwaziri   +7 more
wiley   +1 more source

Frequency and Characterization of Local Ocular Toxicity in Cats Treated With Topical Ophthalmic Cidofovir for Presumptive Feline Herpesvirus‐1 Infection

open access: yesVeterinary Ophthalmology, Volume 29, Issue 1, January 2026.
ABSTRACT Objective To determine the frequency and clinical characteristics of local ocular adverse reactions to topical ophthalmic cidofovir administration in cats with presumptive feline herpesvirus‐1 (FHV‐1) keratoconjunctivitis. Animal Studied In total, 140 cats treated with cidofovir.
Eric C. Ledbetter, Amy J. Morgan
wiley   +1 more source

Bell's palsy: combined treatment of famciclovir and prednisone is superior to prednisone alone

open access: yes, 2008
There is insufficient evidence concerning the efficacy of antiviral treatment of Bell's palsy (BP). We therefore compared the efficacy of prednisone and famciclovir to prednisone treatment alone in BP.
Klockgether, T.   +5 more
core   +1 more source

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