Results 11 to 20 of about 3,303,931 (259)

Predicting the risk of distant metastasis in patients with locally advanced rectal cancer using model based on pre-treatment T2WI-based radiomic features plus postoperative pathological stage

Frontiers in Oncology, 2023
ObjectiveTo assess the prognostic value of a model based on pre-treatment T2WI-based radiomic features and postoperative pathological staging in patients with locally advanced rectal cancer who have undergone neoadjuvant chemoradiotherapy.MethodsRadiomic
Chen Wang, Chen Wang, Jingjing Chen, Nanxin Zheng, Nanxin Zheng, Kuo Zheng, Kuo Zheng, Lu Zhou, Lu Zhou, Qianwen Zhang, Wei Zhang, Wei Zhang   +11 more
doaj   +1 more source

Genetic predisposition to prostate cancer: an update.

, 2021
Improvements in DNA sequencing technology and discoveries made by large scale genome-wide association studies have led to enormous insight into the role of genetic variation in prostate cancer risk.
Eeles, R, Ni Raghallaigh, H
core   +1 more source

Current clinical practice for familial adenomatous polyposis in Japan: A nationwide multicenter study

Annals of Gastroenterological Surgery, 2022
Introduction In Japanese patients with familial adenomatous polyposis (FAP), colectomy tends to be postponed or avoided. Aim This study aimed to clarify the current clinical practice from a Japanese multicenter cohort study database.
Takaaki Matsubara, Naohito Beppu, Masataka Ikeda, Hideyuki Ishida, Yoji Takeuchi, Toshiya Nagasaki, Akinari Takao, Kazuhito Sasaki, Kiwamu Akagi, Tomoya Sudo, Hideki Ueno, Tatsuro Yamaguchi, Naohiro Tomita, Yoichi Ajioka   +13 more
doaj   +1 more source

A comprehensive model for familial breast cancer incorporating BRCA1, BRCA2 and other genes. [PDF]

, 2002
In computing the probability that a woman is a BRCA1 or BRCA2 carrier for genetic counselling purposes, it is important to allow for the fact that other breast cancer susceptibility genes may exist.
P D P Pharoah, D F Easton, Peto, J, J Peto, Stratton, MR, Day, NE, McMullan, G, Antoniou, AC, Easton, DF, N E Day, M R Stratton, A C Antoniou, Pharoah, PDP, B J Ponder, Ponder, BJ, G McMullan   +15 more
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Case report: Obstructive azoospermia as the first presentation of Von Hippel-Lindau disease

Frontiers in Oncology, 2023
We report the case of a 38-year-old man whose diagnostic workup for primary infertility led to the discovery of obstructive azoospermia due to bilateral papillary cystadenoma of the epididymis (PCE). Given the rarity of this finding and because PCE could
Raffaele Scafa, Maurizio Merico, Alfonso Massimiliano Ferrara, Sara Watutantrige Fernando, Pava Srsen, Francesca Schiavi, Stefania Zovato, Alberto Ferlin, Alberto Ferlin   +8 more
doaj   +1 more source

Evaluation of healthcare management issues in the provision of clinical services for familial breast/ovarian cancer [PDF]

, 2009
Electronic version does not contain associated previously published materialDespite there being pragmatic national guidelines for assigning risk to women with a family history of breast cancer, the evidence base is still sparse.
de Azevedo Moreira Reis, Marta
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A tumor focused approach to resolving the etiology of DNA mismatch repair deficient tumors classified as suspected Lynch syndrome

Journal of Translational Medicine, 2023
Routine screening of tumors for DNA mismatch repair (MMR) deficiency (dMMR) in colorectal (CRC), endometrial (EC) and sebaceous skin (SST) tumors leads to a significant proportion of unresolved cases classified as suspected Lynch syndrome (SLS).
Romy Walker, Khalid Mahmood, Jihoon E. Joo, Mark Clendenning, Peter Georgeson, Julia Como, Sharelle Joseland, Susan G. Preston, Yoland Antill, Rachel Austin, Alex Boussioutas, Michelle Bowman, Jo Burke, Ainsley Campbell, Simin Daneshvar, Emma Edwards, Margaret Gleeson, Annabel Goodwin, Marion T. Harris, Alex Henderson, Megan Higgins, John L. Hopper, Ryan A. Hutchinson, Emilia Ip, Joanne Isbister, Kais Kasem, Helen Marfan, Di Milnes, Annabelle Ng, Cassandra Nichols, Shona O’Connell, Nicholas Pachter, Bernard J. Pope, Nicola Poplawski, Abiramy Ragunathan, Courtney Smyth, Allan Spigelman, Kirsty Storey, Rachel Susman, Jessica A. Taylor, Linda Warwick, Mathilda Wilding, Rachel Williams, Aung K. Win, Michael D. Walsh, Finlay A. Macrae, Mark A. Jenkins, Christophe Rosty, Ingrid M. Winship, Daniel D. Buchanan, for the Family Cancer Clinics of Australia   +50 more
doaj   +1 more source

Ethical, social and economic issues in familial breast cancer: a compilation of views from the EC biomed II demonstration project [PDF]

, 1999
: Demand for clinical services for familial breast cancer is continuing to rise across Europe. Service provision is far from uniform and, in most centres, its evolution has been determined by local conditions, specifically by local research ...
Hodgson, S, Haites, N., Stoppa-Lyonnet, D., Eccles, D, Stoppa-Lyonnet, D, Morrison, P., Eccles, D., Møller, P, Steel, M., Chang-Claude, J., Smyth, E., Moller, P., Evans, G.; id_orcid, Haites, N, Caligo, M., Steel, M, Hodgson, S., Vasen, H, Evans, G, Evans, G., Chang-Claude, J, Morrison, P, Smyth, E, Caligo, M, Vasen, H.   +24 more
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Is There a Role for Risk-Reducing Bilateral Breast Surgery in BRCA1/2 Ovarian Cancer Survivors? An Observational Study

Current Oncology, 2023
Background: Risk-reducing surgeries are an option for cancer risk management in BRCA1/2 individuals. However, while adnexectomy is commonly recommended in breast cancer (BC) survivors, risk-reducing bilateral breast surgery (RRBBS) is controversial in ...
Daniela Oliveira, Sofia Fernandes, Isália Miguel, Sofia Fragoso, Fátima Vaz   +4 more
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Juvenile polyposis syndrome might be misdiagnosed as familial adenomatous polyposis: a case report and literature review

BMC Gastroenterology, 2020
Background Juvenile polyposis syndrome (JPS) is a rare disorder characterized by the presence of multiple juvenile polyps in the gastrointestinal tract, and germline mutations in SMAD4 or BMPR1A.
Xian Hua Gao, Juan Li, Zi Ye Zhao, Xiao Dong Xu, Yi Qi Du, Hong Li Yan, Lian Jie Liu, Chen Guang Bai, Wei Zhang   +8 more
doaj   +1 more source