Results 101 to 110 of about 6,501 (209)
This systematic scoping review explores conductive nanocomposite hydrogels for neural tissue engineering(NTE), focusing on composition, cellular interactions, and neural differentiation capabilities. The review synthesizes data from 125 studies, examining important features including commonly used materials, cell types, and differentiation strategies ...
Mohammad Moghaddasi +6 more
wiley +1 more source
Weiwei Yu, Haiqiang Jin, Qian You, Ding Nan, Yining HuangDepartment of Neurology, Peking University First Hospital, Beijing 100034, People’s Republic of ChinaAbstract: Cerebral cavernous malformations (CCMs) are one of the most common types of ...
Yu W, Jin H, You Q, Nan D, Huang Y
doaj
STK25 Loss Augments Anti‐PD‐1 Therapy Efficacy by Regulating PD‐L1 Stability in Colorectal Cancer
This study demonstrates that STK25 depletion facilitates CRC immune escape through the inhibition of PD‐L1 Ser283 phosphorylation‐mediated ubiquitination, and promotes tumor growth. Furthermore, these findings identify STK25 as a potential therapeutic target to trigger antitumor immunity and promote immunotherapy efficacy. Abstract Tumor immune evasion
Xiaowen Qiao +20 more
wiley +1 more source
Blue rubber-bleb nevus syndrome: report of a familial case with a dural arteriovenous fistula [PDF]
We report a case of a 45-year-old woman known to have a familial form of blue rubber-bleb nevus syndrome (BRBNS). The patient developed severe occipital headaches and bilateral retroauricular bruits.
Barbosa, V +3 more
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Summary: Cerebral cavernous malformation (CCM) is a neurovascular disease distinguished by clusters of leaky, mulberry-like blood vessels. KRIT1 bi-allelic loss-of-function mutations in endothelial cells are known to trigger brain cavernomas; however ...
Maximiliano Arce +21 more
doaj +1 more source
Cerebral Cavernous Malformations: An Update on Prevalence, Molecular Genetic Analyses, and Genetic Counselling [PDF]
Based on the latest gnomAD dataset, the prevalence of symptomatic hereditary cerebral cavernous malformations (CCMs) prone to cause epileptic seizures and stroke-like symptoms was re-evaluated in this review and calculated to be 1:5,400-1:6,200 ...
Felbor, Ute +3 more
core +1 more source
Familial Cerebral Cavernous Malformations: A Case Report
Aims: Describe the main imaging findings of familial cerebral cavernous malformations. Presentation of Case: This is the clinical case of a 68-year-old woman with a history of type 2 diabetes mellitus and long-standing systemic arterial hypertension. She presents to the neurology outpatient clinic reporting dizziness, temporal-spatial disorientation ...
Jesús Octavio Tafoya Hernández +5 more
openaire +1 more source
Functional outcome of microsurgical clipping compared to endovascular coiling [PDF]
Objective: Endovascular coiling has been used increasingly as an alternative to neurosurgical clipping for treating subarachnoid hemorrhage secondary to aneurysm rupture.
Premananda Raja , Murugesu
core
Creation of a database for evaluating the effect of genetic intellectual property on genetic diagnostic testing [PDF]
Thesis (S.B.)--Massachusetts Institute of Technology, Dept. of Mechanical Engineering, 2006.Includes bibliographical references (leaves 33-34).In this study, we explore the impact of gene-based patents on the pricing and availability of genetic ...
Murray, Philip (Philip E.)
core
Congenital vascular malformations update [PDF]
Presently, there is controversy and misconception in the diagnosis and management of most congenital vascular malformations. The aim of this manuscript is to identify the current knowledge of these poorly understood and relatively uncommon pathologies ...
Albores Figueroa, Rosemberg +4 more
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