Results 81 to 90 of about 6,501 (209)

Vascularised Brain Organoids: Engineering Strategies and Neurobiological Applications

Cell Proliferation, Volume 59, Issue 3, March 2026.
This review highlights emerging strategies to engineer vascularized brain organoids—including endothelial co‐culture, genetic induction, perfusion systems, and in vivo transplantation—and their applications in modelling neurovascular diseases, evaluating BBB drug delivery, and advancing regenerative medicine.
Yeajin Song, Hyejin Jo, Seokchan Jeong, Inseon Kim, Seunghun S. Lee   +4 more
wiley   +1 more source

Developing a Randomised Efficacy PREcision medicine Platform trial design for Cavernomas: the CARE PREP study

Efficacy and Mechanism Evaluation
Background Symptomatic cerebral cavernous malformations are a rare sporadic or familial disease, which may cause haemorrhagic strokes or epileptic seizures.
Rustam Al-Shahi Salman, Kasia Adamczuk, Richard A Parker, Christopher J Weir, Roberto Latini, Helen Kim, David White, Helen Evans, Jana Bergholtz, Cornelia Lee, Carlos Casaus   +10 more
doaj   +1 more source

Rates and characteristics of radiographically detected intracerebral cavernous malformations after cranial radiation therapy in pediatric cancer patients. [PDF]

, 2014
Rates and characteristics of intracerebral cavernous malformations after cranial radiation therapy remain poorly understood. Herein we report on intracerebral cavernous malformations detected on follow-up imaging in pediatric cancer patients who received
Chettout, Nassim, Cotter, Jennifer, Fullerton, Heather, Gastelum, Erica, Haas-Kogan, Daphne A, Hess, Christopher, Hills, Nancy, Mueller, Sabine, Randazzo, Dominica, Roddy, Erika, Sear, Katherine   +10 more
core   +2 more sources

Cerebrovascular Malformations Associated With Hereditary Hemorrhagic Telangiectasia and HHT‐Like Syndromes: A Comparative Overview

European Journal of Neurology, Volume 33, Issue 2, February 2026.
Hereditary hemorrhagic telangiectasia (HHT) and several HHT‐like syndromes, including Wyburn–Mason, Cobb, Klippel–Trénaunay, Parkes Weber, neurofibromatosis type 1, PHACE(S), capillary malformation–AVM (CM‐AVM), Juvenile polyposis/HHT overlap, HHT type 5, PTEN hamartoma tumor syndrome, and blue rubber bleb nevus syndrome, share overlapping ...
Matteo Palermo, Carmelo Lucio Sturiale
wiley   +1 more source

Cavernous Malformations of the Brain: Natural History and Surgical Outcomes

Journal of the Pakistan Medical Association
Cerebral cavernous malformations (CCM) are rare, benign vascular anomalies of the central nervous system with a prevalence of 0.5–0.8%. While often discovered incidentally, they may present with seizures, headaches, focal neurological deficits, or ...
Noman Ahmed, Zanib Javed, Muhammad Shahzad Shamim   +2 more
doaj   +1 more source

Inherited cavernous malformations of the central nervous system: clinical and genetic features in 19 Swiss families [PDF]

, 2018
Cavernous malformations (CCMs) are benign, well-circumscribed, and mulberry-like vascular malformations that may be found in the central nervous system in up to 0.5% of the population. Cavernous malformations can be sporadic or inherited.
Andermann, F., Baumann, C., Baumgartner, R., Bonassin, F., Georgiadis, D., Graeni, C., Merlo, A., Rouleau, G., Siegel, A., Stepper, F., Sturzenegger, M., Verlaan, D.   +11 more
core  

Actualización en malformaciones venosas [PDF]

, 2010
Venous malformations represent 2/3rds of all vascular malformations and are frequently much more complex than they appear to be. Patients with large venous malformations require a deep analytical and radiological study, as well as specific treatment ...
Aguado, L. (Leyre), Redondo, P. (Pedro)
core   +1 more source

Automated algorithm for counting microbleeds in patients with familial cerebral cavernous malformations [PDF]

Neuroradiology, 2017
Familial cerebral cavernous malformation (CCM) patients present with multiple lesions that can grow both in number and size over time and are reliably detected on susceptibility-weighted imaging (SWI). Manual counting of lesions is arduous and subject to high variability. We aimed to develop an automated algorithm for counting CCM microbleeds (lesions
Zou, Xiaowei, Hart, Blaine L, Mabray, Marc, Bartlett, Mary R, Bian, Wei, Nelson, Jeffrey, Morrison, Leslie A, McCulloch, Charles E, Hess, Christopher P, Lupo, Janine M, Kim, Helen   +10 more
openaire   +4 more sources

The Most Common Comorbidities in Dandy-Walker Syndrome Patients: A Systematic Review of Case Reports. [PDF]

, 2017
OBJECTIVE: Dandy-Walker syndrome (DWS) is a rare neurologic multi-entity malformation. This review aimed at reporting its main nonneurologic comorbidities.
Aluclu MU, Amin OS, Antonis A. Kousoulis, Arai M, Ben Hamouda H, Bokhari I, Buonaguro EF, Caglayan AO, Cakmak A, Chen CP, Cultrera F, de Brito Henriques JG, Dinakar C, Emelina Stambolliu, Eslami Shahre Babaki M, Ghosh A, Gulcan YH, Gveric-Ahmetasevic S, Hammond CJ, Hussain Z, Kimonas Kontokostas, Koul RL, Kurdi ME, Lin MC, Mancini TI, Maria Dakoutrou, McClelland S, McCormack WM, Muzumdar DP, Myrsini Ioakeim-Ioannidou, Na M, Nyberg DA, Richter EO, Su PH, Titlic M, Unal O, Warwick CT, Yoder BJ   +37 more
core   +2 more sources

Molecular Diagnosis in a Specialised Neurogenetic Clinic With Access to Whole‐Genome Sequencing

Acta Neurologica Scandinavica, Volume 2026, Issue 1, 2026.
Background Rare diseases, collectively affecting 1 in 17 people in the United Kingdom and Ireland, require coordinated care. Specialised multidisciplinary clinics offer a streamlined approach for diagnosis and management of rare neurogenetic disorders.
Patrick B. Moloney, Nicholas W. Wood, Rob Rouhl   +2 more
wiley   +1 more source