Results 61 to 70 of about 3,068 (175)

Medication intake and hemorrhage risk in patients with Familial Cerebral Cavernous Malformations

Brain and Spine, 2022
OBJECTIVE The objective of this study was to analyze the impact of medication intake on hemorrhage risk in patients with familial cerebral cavernous malformation (FCCM). METHODS The authors’ institutional database was screened for patients with FCCM who had been admitted to their department between 2003 and 2020.
Santos, Alejandro N., Rauschenbach, Laurèl, Saban, Dino, Chen, Bixia, Lenkeit, Annika, Gull, Hanah Hadice, Rieß, Christoph, Deuschl, Cornelius, Schmidt, Börge, Jabbarli, Ramazan, Wrede, Karsten, Zhu, Yuan, Frank, Benedikt, Sure, Ulrich, Dammann, Philipp   +14 more
openaire   +4 more sources

Neurocognitive, behavioral, and treatment burden as key predictors of parental stress in pediatric epilepsy

Epilepsia, Volume 66, Issue 12, Page 4960-4971, December 2025.
Parental stress is linked to child cognitive impairment, internalizing symptoms, complex treatments, and lower caregiver education. No gender differences were found, though most caregivers were mothers. Findings suggest the need for support beyond seizure control.
Cinzia Correale, Mattia Mercier, Simona Cappelletti, Nicola Pietrafusa, Chiara Falamesca, Elisabetta Collalti, Giusy Carfi’ Pavia, Costanza Calabrese, Marina Trivisano, Luca De Palma, Francesca Cirulli, Nicola Specchio   +11 more
wiley   +1 more source

Update and new advances in fertility preservation and cancer

CA: A Cancer Journal for Clinicians, Volume 75, Issue 6, Page 602-629, November/December 2025.
Abstract Adolescents and young adults with a cancer diagnosis face unique challenges during treatment and into survivorship related to fertility and family building. This review provides an updated overview of the impact of cancer and its associated treatments, including novel treatments in male and female fertility.
Gwendolyn P. Quinn, Michelle Bayefsky, Brooke Cherven, Lauren V. Ghazal, Kara N. Goldman, Nina Francis Levin, Leena Nahata, Bobby Najari, Sameer Thakker, Daniel R. Greenberg, Joshua A. Halpern, Susan T. Vadaparampil   +11 more
wiley   +1 more source

PIEZO Force Sensing in Vascular Biology: An Explosion of New Knowledge, Concepts and Opportunity

Advanced Science, Volume 12, Issue 41, November 6, 2025.
Knowledge of the remarkable mechanical force sensing and electrically transducing PIEZO1 and PIEZO2 channels is discussed across vascular biology and its cell types from the embryonic to adult stages in health, disease and old age. How the channels work, relate to other factors and signal for tissue responses to mechanical forces is debated.
David J Beech
wiley   +1 more source

Inherited cavernous malformations of the central nervous system: clinical and genetic features in 19 Swiss families [PDF]

, 2018
Cavernous malformations (CCMs) are benign, well-circumscribed, and mulberry-like vascular malformations that may be found in the central nervous system in up to 0.5% of the population. Cavernous malformations can be sporadic or inherited.
Andermann, F., Baumann, C., Baumgartner, R., Bonassin, F., Georgiadis, D., Graeni, C., Merlo, A., Rouleau, G., Siegel, A., Stepper, F., Sturzenegger, M., Verlaan, D.   +11 more
core  

Conductive Nanocomposite Hydrogels for Neural Tissue Engineering: A Systematic Scoping Review of Recent Trends

Advanced Science, Volume 12, Issue 38, October 13, 2025.
This systematic scoping review explores conductive nanocomposite hydrogels for neural tissue engineering(NTE), focusing on composition, cellular interactions, and neural differentiation capabilities. The review synthesizes data from 125 studies, examining important features including commonly used materials, cell types, and differentiation strategies ...
Mohammad Moghaddasi, Busra Oktay, Ayse Betul Bingol, Reyhan Yanikoglu, Meryem Muslu, Ibrahim T Ozbolat, Cem Bulent Ustundag   +6 more
wiley   +1 more source

The Most Common Comorbidities in Dandy-Walker Syndrome Patients: A Systematic Review of Case Reports. [PDF]

, 2017
OBJECTIVE: Dandy-Walker syndrome (DWS) is a rare neurologic multi-entity malformation. This review aimed at reporting its main nonneurologic comorbidities.
Aluclu MU, Amin OS, Antonis A. Kousoulis, Arai M, Ben Hamouda H, Bokhari I, Buonaguro EF, Caglayan AO, Cakmak A, Chen CP, Cultrera F, de Brito Henriques JG, Dinakar C, Emelina Stambolliu, Eslami Shahre Babaki M, Ghosh A, Gulcan YH, Gveric-Ahmetasevic S, Hammond CJ, Hussain Z, Kimonas Kontokostas, Koul RL, Kurdi ME, Lin MC, Mancini TI, Maria Dakoutrou, McClelland S, McCormack WM, Muzumdar DP, Myrsini Ioakeim-Ioannidou, Na M, Nyberg DA, Richter EO, Su PH, Titlic M, Unal O, Warwick CT, Yoder BJ   +37 more
core   +2 more sources

STK25 Loss Augments Anti‐PD‐1 Therapy Efficacy by Regulating PD‐L1 Stability in Colorectal Cancer

Advanced Science, Volume 12, Issue 39, October 20, 2025.
This study demonstrates that STK25 depletion facilitates CRC immune escape through the inhibition of PD‐L1 Ser283 phosphorylation‐mediated ubiquitination, and promotes tumor growth. Furthermore, these findings identify STK25 as a potential therapeutic target to trigger antitumor immunity and promote immunotherapy efficacy. Abstract Tumor immune evasion
Xiaowen Qiao, Pu Xing, Hao Hao, Jiangbo Chen, Lin Song, Yifan Hou, Xinying Yang, Kai Weng, Jie Chen, Pin Gao, Tongkun Song, Hong Yang, Tianqi Liu, Yumeng Ran, Bo Chen, Wei Zhao, Jiabo Di, Zaozao Wang, Jun Zhang, Xiangqian Su, Beihai Jiang   +20 more
wiley   +1 more source

Chromosome 3q22.2‐q26.2 Interstitial Deletion in a Patient With Wisconsin Syndrome, Blepharophimosis‐Ptosis‐Epicanthus Inversus Syndrome, Dandy‐Walker Malformation, Pierre Robin Sequence, and Recurrent Infections

American Journal of Medical Genetics Part A, Volume 197, Issue 10, October 2025.
ABSTRACT Wisconsin syndrome is a very rare genetic condition characterized by coarse facies, prominent nasal tip, bushy high arched/upsweeping eyebrows, and a full/everted lower lip. Deletion of chromosome 3q24q25 region is considered critical for its manifestation.
Pankaj Prasun, Sonja Henry, Vivek Balasubramaniam   +2 more
wiley   +1 more source

Multiple cerebral cavernous malformations in association with a Dubowitz-like syndrome. [PDF]

, 2020
Cerebral cavernous malformations (CCMs) are proliferative sinusoidal vascular lesions and are the most common vascular malformations of the brain. They can occur sporadically or secondary to an underlying genetic predisposition where multiple lesions are
Gurusinghe, NT, Mostofi, A
core   +1 more source