Familial hemiplegic migraine type 2: a case report of an adolescent with ATP1A2 mutation [PDF]
Frontiers in NeurologyThis study presents a case report of a male adolescent diagnosed with familial hemiplegic migraine type 2 (FHM2), an autosomal dominant inheritance disorder caused by ATP1A2 mutation.
Hui Zhang +7 more
exaly +4 more sources
Familial Hemiplegic Migraine Type 3 (FHM3) With an SCN1A Mutation in a Chinese Family: A Case Report [PDF]
Frontiers in Neurology, 2018 Familial hemiplegic migraine (FHM) is a rare, monogenic, autosomal dominant subtype of migraine, in which three genes, CACNA1A, ATP1A2, and SCN1A, are currently known to be involved.
Na Shao +5 more
doaj +4 more sources
CACNA1A-p.Thr501Met mutation associated with familial hemiplegic migraine: a family report [PDF]
The Journal of Headache and Pain, 2021 Background and aims Hemiplegic migraine (HM) is a rare form of migraine characterized by the presence of a motor and other types of aura. HM can be sporadic or familial.
Marina Romozzi +6 more
doaj +2 more sources
Serial magnetic resonance imaging findings during severe attacks of familial hemiplegic migraine type 2: a case report [PDF]
BMC Neurology, 2021 Background Hemiplegic migraines represent a heterogeneous disorder with various presentations. Hemiplegic migraines are classified as sporadic or familial based on the presence of family history, but both subtypes have an underlying genetic etiology ...
David Fear, Misha Patel, Ramin Zand
doaj +2 more sources
Changes in Plasma Lipid Levels Following Cortical Spreading Depolarization in a Transgenic Mouse Model of Familial Hemiplegic Migraine [PDF]
Metabolites, 2022 Metabolite levels in peripheral body fluids can correlate with attack features in migraine patients, which underscores the potential of plasma metabolites as possible disease biomarkers.
Inge C. M. Loonen +6 more
doaj +2 more sources
Identification of Copy Number Variations in Familial Hemiplegic Migraine Genes in Suspected Hemiplegic Migraine Patients [PDF]
BiomedicinesBackground: Familial hemiplegic migraine (FHM) is a rare and severe form of migraine disorder featuring aura symptoms that include hemiplegia during attacks.
Thais Zielke +4 more
doaj +2 more sources
Familial Hemiplegic Migraine With Progressive Cerebellar Ataxia Caused by a p.Thr666Met CACNA1A Gene Mutation in a Chinese Family [PDF]
Frontiers in Neurology, 2019 Here, we describe the first case of familial hemiplegic migraine type 1 (FHM1) resulting from a T666M mutation in the CACNA1A gene of a Chinese individual.
Mengmeng Li +6 more
doaj +2 more sources
Dissociated neurovascular dynamics in ATP1A2-related familial hemiplegic migraine mimicking acute ischemic stroke [PDF]
BMC NeurologyBackground Hemiplegic migraine (HM) is a rare migraine subtype with motor aura. Familial hemiplegic migraine type 2 (FHM2), caused by ATP1A2 mutations, often mimics acute stroke, making early neuroimaging differentiation critical. While dynamic perfusion
Gha-hyun Lee, Jiyoung Kim, Jae Wook Cho
doaj +2 more sources
Familial Hemiplegic Migraine with Severe Attacks: A New Report with ATP1A2 Mutation [PDF]
Case Reports in Neurological Medicine, 2016 Introduction. Familial hemiplegic migraine (FHM) is a rare disorder characterized by migraine attacks with motor weakness during the aura phase. Mutations in CACNA1A, ATP1A2, SCN1A, and PRRT2 genes have been described. Methods.
E. Martínez +6 more
doaj +2 more sources
Gain of Function for the SCN1A/hNav1.1-L1670W Mutation Responsible for Familial Hemiplegic Migraine [PDF]
Frontiers in Molecular Neuroscience, 2018 The SCN1A gene encodes for the voltage-dependent Nav1.1 Na+ channel, an isoform mainly expressed in GABAergic neurons that is the target of hundreds of epileptogenic mutations.
Sandra Dhifallah +5 more
doaj +2 more sources