Results 61 to 70 of about 234,110 (135)

Transient nonverbal learning disorder in a child suffering from Familial Hemiplegic Migraine

, 2011
Objective: To study the link between nonverbal learning disorder and right cerebral hemisphere dysfunction due to migraine attack in a case of Familial Hemiplegic Migraine.
Barbara Podestà, Daniela Marenco, Stefano Calzolari, Eleonora Briatore, Andrea Boghi   +4 more
core   +1 more source

Upregulation of IL-1 Receptor Antagonist in a Mouse Model of Migraine

Brain Sciences, 2019
Migraine is a disorder characterized by attacks of monolateral headaches, often accompanied by nausea, vomiting, and photophobia. Around 30% of patients also report aura symptoms.
Salvo Danilo Lombardo, Emanuela Mazzon, Maria Sofia Basile, Eugenio Cavalli, Placido Bramanti, Riccardo Nania, Paolo Fagone, Ferdinando Nicoletti, Maria Cristina Petralia   +8 more
doaj   +1 more source

Familial hemiplegic migraine: a ion channel disorder

, 2001
At present, little information is available on the genetics of common migraines, most likely to be considered a multifactorial disease. Recently, the CACNA1A gene encoding the brain-specific P/Q type calcium channel alpha(1) subunit, has been cloned and ...
FERRARI, M., CARRERA, P., STENIRRI, S., BATTISTINI, S.   +3 more
core   +1 more source

Defective glutamate and K+ clearance by cortical astrocytes in familial hemiplegic migraine type 2

EMBO Molecular Medicine, 2016
Migraine is a common disabling brain disorder. A subtype of migraine with aura (familial hemiplegic migraine type 2: FHM2) is caused by loss‐of‐function mutations in α2 Na+,K+ ATPase (α2 NKA), an isoform almost exclusively expressed in astrocytes in ...
Clizia Capuani, Marcello Melone, Angelita Tottene, Luca Bragina, Giovanna Crivellaro, Mirko Santello, Giorgio Casari, Fiorenzo Conti, Daniela Pietrobon   +8 more
doaj   +1 more source

Familial Hemiplegic Migraine

, 2007
Familial hemiplegic migraine (FHM) is a rare and genetically heterogeneous autosomal dominant subtype of migraine with aura. Mutations in the genes CACNA1A and SCAA 1A, encoding the pore-forming alpha(1) subunits of the neuronal voltage-gated Ca2 ...
PIETROBON, DANIELA
core   +1 more source

Biochemical characterization of sporadic/familial hemiplegic migraine mutations [PDF]

, 2014
Contains fulltext : 133904.pdf (Publisher’s version ) (Open Access)Sporadic hemiplegic migraine type 2 (SHM2) and familial hemiplegic migraine type 2 (FHM2) are rare forms of hemiplegic migraine caused by mutations in the Na(+),K ...
Koenderink, J.B., Koenderink, Jan B., Weigand, K.M., Weigand, Karl M., Russel, F.G., Russel, Frans G.M., Swarts, Herman G.P., Swarts, H.G.P.   +7 more
core   +2 more sources

Targeted next generation sequencing identifies a genetic spectrum of DNA variants in patients with hemiplegic migraine

Cephalalgia Reports, 2019
Objective: Hemiplegic migraine in both familial (FHM) and sporadic (SHM) forms is a rare subtype of migraine with aura that can be traced to mutations in the CACNA1A , ATP1A2 and SCN1A genes.
Neven Maksemous, Robert A Smith, Heidi G Sutherland, Bridget H Maher, Omar Ibrahim, Garth A Nicholson, Elisabeth P Carpenter, Rod A Lea, M Zameel Cader, Lyn R Griffiths   +9 more
doaj   +1 more source

Two novel families with hemiplegic migraine caused by recurrent SCN1A mutation p.F1499L

, 2017
Background Familial hemiplegic migraine type 3 is a monogenic subtype of migraine caused by missense mutations in the neuronal voltage-gated sodium channel gene SCN1A, with 10 different mutations reported so far.
Eva Auffenberg, Victoria Schubert, Tobias Freilinger, Saskia Biskup, Karin Jurkat-Rott   +4 more
core   +1 more source

Genetic mouse models of migraine

The Journal of Headache and Pain, 2019
Mouse models of rare monogenic forms of migraine provide a unique experimental system to study the cellular and circuit mechanisms of the primary brain dysfunctions causing a migraine disorder.
Daniela Pietrobon, K. C. Brennan
doaj   +1 more source

An Unusual Presentation of Sporadic Hemiplegic Migraine: A Case Report [PDF]

Journal of Clinical and Diagnostic Research
Sporadic Hemiplegic Migraine (SHM) is a rare subtype of migraine with recurrent attacks of reversible motor weakness alongside with visual, sensory and speech symptoms.
R Priyanka, Vidya Krishnamurthy, Uday Kumar   +2 more
doaj   +1 more source