Results 11 to 20 of about 340,370 (339)

Familial hypercholesterolemia. [PDF]

Circulation, 2020
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Joana Rita Chora, Ana Margarida Medeiros, A. C. Alves, Mafalda Bourbon   +3 more
semanticscholar   +3 more sources

Real‐World Effectiveness of PCSK9 Inhibitors in Reducing LDL‐C in Patients With Familial Hypercholesterolemia in Italy: A Retrospective Cohort Study Based on the AIFA Monitoring Registries

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2023
Background Information on the real‐world use of proprotein convertase subtilisin kexin 9 inhibitors (PCKS9is) in familial hypercholesterolemia are limited.
Marcello Arca, Simone Celant, Pier Paolo Olimpieri, Antonietta Colatrella, Luca Tomassini, Laura D'Erasmo, Maurizio Averna, Alberto Zambon, Alberico Luigi Catapano, Pierluigi Russo   +9 more
doaj   +2 more sources

Homozygous Familial Hypercholesterolemia

Journal of Atherosclerosis and Thrombosis, 2021
Familial hypercholesterolemia (FH) is an inherited disorder with retarded clearance of plasma LDL caused by mutations of the genes involved in the LDL receptor-mediated pathway and most of them exhibit autosomal dominant inheritance.
A. Nohara, H. Tada, M. Ogura, Sachiko Okazaki, K. Ono, H. Shimano, H. Daida, Kazushige Dobashi, Toshio Hayashi, M. Hori, K. Matsuki, T. Minamino, S. Yokoyama, M. Harada‐Shiba   +13 more
semanticscholar   +4 more sources

Prevalence of Familial Hypercholesterolemia Among the General Population and Patients With Atherosclerotic Cardiovascular Disease

Circulation, 2020
Supplemental Digital Content is available in the text. Background: Contemporary studies suggest that familial hypercholesterolemia (FH) is more frequent than previously reported and increasingly recognized as affecting individuals of all ethnicities and ...
Christophe A T Stevens, Mansour Taghavi Azar Sharabiani   +1 more
exaly   +2 more sources

Familial Hypercholesterolemia

罕见病研究, 2023
Familial hypercholesterolemia (FH) is a group of autosomal co-dominant genetic diseases mainly characterized by abnormal low-density lipoprotein related metabolism.
FENG Siqin, TANG Muyun, WU Wei, ZHANG Shuyang   +3 more
doaj   +3 more sources

Familial hypercholesterolemia

Indian Heart Journal
Familial hypercholesterolemia is a common genetic disorder of autosomal inheritance associated with elevated LDL-cholesterol. It is estimated to affect 1:250 individuals in general population roughly estimated to be 5 million in India.
J.P.S. Sawhney, Kushal Madan
doaj   +3 more sources

Lipoprotein metabolism in familial hypercholesterolemia [PDF]

Journal of Lipid Research, 2021
Familial hypercholesterolemia (FH) is one of the most common genetic disorders in humans. It is an extremely atherogenic metabolic disorder characterized by lifelong elevations of circulating LDL-C levels often leading to premature cardiovascular events.
K. Chemello, J. García-Nafría, A. Gallo, César Martín, G. Lambert, D. Blom   +5 more
semanticscholar   +8 more sources

Recent Advances on Familial Hypercholesterolemia in Children and Adolescents

Biomedicines, 2022
Familial hypercholesterolemia is a common autosomal hereditary disorder characterized by elevated concentrations of low-density lipoprotein cholesterol and the development of premature atherosclerosis and cardiovascular disease.
Francesca Mainieri, Veronica Maria Tagi, Francesco Chiarelli   +2 more
doaj   +2 more sources

Healthcare activities before familial hypercholesterolemia diagnosis: a nationwide register-based study in Denmark [PDF]

BMC Primary Care
Background Familial hypercholesterolemia is a common yet underdiagnosed genetic disorder that significantly increases the risk of premature atherosclerotic cardiovascular disease.
Simon Graff, Kirsten Høj, Bo Christensen, Flemming Bro, Helle Lynge Kanstrup, Henrik Schou Pedersen   +5 more
doaj   +2 more sources

Familial Hypercholesterolemia

Gomal Journal of Medical Sciences, 2004
Abnormalities in the lipid profile though uncommon in pediatric practice pose an increased risk for developing heart disease. Studies suggest that adult cardiovascular disease has its roots in children and young adults. A significant correlation between atherosclerotic changes in children and young adults and total and LDL cholesterol levels also ...
Sheikh Muhammad Nazir
doaj   +3 more sources