Results 251 to 260 of about 340,370 (339)

Missed and Misdiagnosed: Precision Medicine Approaches to Screening for Familial Hypercholesterolemia and Lipoprotein(a). [PDF]

JACC Adv
Helm BM, Huerta V, Clary JM.
europepmc   +1 more source

The Role and Therapeutic Potential of Voltage‐Gated Potassium Channel Kv1.3 in Metabolism‐Related Disorders

iNew Medicine, Volume 2, Issue 2, June 2026.
ABSTRACT Over the past three decades, the global burden of common metabolic diseases such as obesity, diabetes, and atherosclerosis has steadily increased, becoming a serious public health issue that poses a major threat to human health worldwide. Potassium channels, particularly the voltage‐gated Kv1.3 subtype, serve as critical regulators of cellular
Wenjun Zhen, Junda Liu, Xixi Chen, Shi Chen, Yuanyuan Tian, Baoming Wu, Fengxia Yan   +6 more
wiley   +1 more source

Therapeutic Plasma Exchange and Evinacumab for Homozygous Familial Hypercholesterolemia. [PDF]

JACC Case Rep
Raygani S, Sykes AV, Sanchez AP, Witztum JL, Wilkinson MJ.   +4 more
europepmc   +1 more source

Vascular Calcification: Mechanisms, Models, and Therapies

iNew Medicine, Volume 2, Issue 2, June 2026.
ABSTRACT Vascular calcification represents an active multifactorial process that mirrors several key features of skeletal bone mineralization. Clinically, it is characterized by diminished arterial compliance and increased arterial wall stiffness, both of which serve as independent predictors of significant adverse cardiovascular events.
Wenya Zhu, Shu Yang, Ziyi Chen, Xiaoxiao Yang, Zhen Liang, Yuanli Chen   +5 more
wiley   +1 more source

Consequences of Late Diagnosis and Insufficient Cholesterol Treatment in Women With Heterozygous Familial Hypercholesterolemia. [PDF]

JACC Case Rep
Santos RD.
europepmc   +1 more source

The Clinical Pathway Initiative: Identifying role relevant competencies in genomic pathways

Journal of Genetic Counseling, Volume 35, Issue 3, June 2026.
Abstract Mainstreaming genomic medicine creates the challenge of ensuring confidence and competence in the healthcare workforce. The Clinical Pathway Initiative (CPI), led by the NHS Genomics Education Programme, maps competencies and educational resources to clinical pathways where genomics is used to deliver care.
Lianne Gompertz, Danielle Bogue, Judith Hayward, Melanie Watson, Edward Miller, Kate Tatton‐Brown   +5 more
wiley   +1 more source

Circadian Immunity and Vascular Inflammation in Cardiovascular Disease Chronotherapy Windows: Time for a Re‐Assessment

Med Research, Volume 2, Issue 2, Page 236-279, June 2026.
ABSTRACT Circadian rhythms orchestrate cardiovascular physiology by regulating immune and inflammatory pathways. Disruption of these rhythms profoundly alters vascular homeostasis, thereby promoting the onset and progression of cardiovascular diseases (CVD).
Tian Zhang, Ge Zhang, Tian‐Ding Liu, Tianshu Gu, Fengyi Yu, Pengyuan Xu, Wunan Mi, Xuanjiang Zhao, Qian Guo, Honglin Zheng, Taiqi Zhao, Qiang Li, Di Lu, Mingxuan Duan, Chaoyang Yu, Ruhao Wu, Shiqian Zhang, Haonan Zhang, Zeyu Wang, Youyang Zheng, Yan Xiao, Zenglei Zhang, Ge Zhang   +22 more
wiley   +1 more source

Novel Therapies, Residual Risk, Familial Hypercholesterolemia, and Digital Tools: Multispecialty Insights from a Dyslipidemia Management Survey. [PDF]

J Clin Med
Mesquita-Lousada A, Rocha-Melo-Sousa A, Teixeira C, Guimarães TR, Marques-Vieira M, Andrade JP, Ribeiro H, Neiva-Sousa M, Rocha-Neves J.   +8 more
europepmc   +1 more source

Comprehensive Evidence for Mortality and Underlying Morbidity Related to Visceral Fat Distribution

Med Research, Volume 2, Issue 2, Page 214-226, June 2026.
ABSTRACT Linking obesity to mortality is an intriguing and controversial topic. This study tried to comprehensively assess 8 adiposity surrogates and mortality association among middle‐to‐old‐aged adults to identify a superior one, and explore explanatory disorders. Data sources included the National Health and Nutrition Examination Survey (NHANES), UK
Haolong Zhou, Danyang Ling, Qin Huang, Jiaojun Liang, Guanhua Su, Zhangbo Cui, Ziwei Chen, Xiaowen Ma, Zhou Jiang, Shuo Zheng, Haodong Tian, Qi Wang   +11 more
wiley   +1 more source

Subclassification of Phenotypic Homozygous Familial Hypercholesterolemia. [PDF]

JACC Asia
Tada H, Harada-Shiba M.
europepmc   +1 more source