Results 41 to 50 of about 5,699 (211)

Familial Mediterranean fever in two brothers aged seven and five years old [PDF]

Journal of Nephropathology
Familial Mediterranean fever (FMF) is an inherited disease characterized by fever and intermittent abdominal pain. Due to amyloid deposits in the kidneys and gastrointestinal tract, untreated FMF can lead to severe complications such as end-stage renal ...
Hedayat Heydarizadeh, Mohammad Moradi, Mojtaba Zare, Samaneh Tahmasebi Ghorabi, Seyed Hossein Hosseini   +4 more
doaj   +1 more source

A large pericardial effusion and bilateral pleural effusions as the initial manifestations of Familial Mediterranean Fever [PDF]

, 2015
Familial Mediterranean Fever (FMF) is a condition characterized by recurrent febrile poly-serositis. Typical presentations of the disease include episodes of fever, abdominal pain and joint pains. Chest pain is a less common presentation.
Mallia, Carmel, Mifsud, Simon, Cassar Demarco, Daniela, Coleiro, Bernard, Schembri, Emma Louise   +4 more
core  

Age‐Dependent Differences in Canakinumab Safety: A Comprehensive Pharmacovigilance Analysis Using the FAERS Database

Pharmacology Research &Perspectives, Volume 14, Issue 3, June 2026.
ABSTRACT While the efficacy of canakinumab, an anti‐interleukin‐1β monoclonal antibody, is well‐established, its safety profile, particularly across different age groups, remains inadequately explored. Using the FDA Adverse Event Reporting System (FAERS) database, this study evaluated postmarketing safety by analyzing adverse event (AE) reports from ...
Youyang Wang, Ngasin Lam, Xiaoming Huang, Yang Jiao   +3 more
wiley   +1 more source

Concurrent TNFRSF1A R92Q and pyrin E230K mutations in a child with multiple sclerosis [PDF]

, 2010
We report a 16-year-old female patient with a severe course of multiple sclerosis and concomitant symptoms suggestive of a hereditary autoinflammatory disease.
K Huss, R Hohlfeld, Kümpfel, T., T Kümpfel, Heinen, F., Mueller-Felber, W., A Blaschek, Blaschek, A., Huss, K., Hohlfeld, R., F Heinen, Blaschek, Astrid, Lohse, P., Borggraefe, I., P Lohse, W Mueller-Felber, I Borggraefe   +16 more
core   +1 more source

A Randomized Trial to Investigate the Effects of Low‐Dose Colchicine in Patients with Hypertension: Rationale and Design of the COlchicine and HypERtENsion Trial (COHERENT)

The Journal of Clinical Hypertension, Volume 28, Issue 6, June 2026.
ABSTRACT Hypertension is a prevalent and significant risk factor for cardiovascular disease (CVD). The immune system and inflammatory response are involved in the pathophysiology of hypertension. We hypothesize that treating hypertension with colchicine on top of standard therapy, will decrease pulse wave velocity (PWV), left ventricular mass, cardiac ...
Adam Femerling Langhoff, Niklas Dyrby Johansen, Marie Frimodt‐Møller, Ahmad Sajadieh, Tina Ken Schramm, Thomas A. Jepps, Tor Biering‐Sørensen   +6 more
wiley   +1 more source

Heterozygous MEFV Mutation Leading to Renal Failure: A Case Study

Global Pediatric Health
Familial Mediterranean fever (FMF) is an autosomal recessive disorder, particularly common in the Mediterranean area. Mutations in the MEVF gene cause it. AA Amyloidosis is the most severe complication of FMF leading to chronic renal failure. We describe
Souhaila El Gazzane MD, Amine Ichane MD, Chaimae Nahi MD, Khadija Mouaddine MD, Bouchra Chkirate MD, PhD, Aziza Guennoun MD, Najat Oulahiane MD, Hassan Ait Ouamar MD, PhD, Lamiaa Rouas MD, PhD   +8 more
doaj   +1 more source

Colchicine-and Clarithromycin-Induced Rhabdomyolysis in a Hemodialysis Patient with Familial Mediterranean Fever

Turkish Journal of Nephrology, 2019
Familial Mediterranean fever (FMF) is an autosomal recessive hereditary disease characterized by recurrent attacks of fever, usually accompanied by sterile polyserositis. Although colchicine is the main medical treatment option for FMF, potential adverse
Amir Hossein ABEDİ, Eray EROĞLU, İsmail KOÇYİĞİT, Aydın ÜNAL, Murat Hayri SİPAHİOĞLU, Bülent TOKGÖZ, Oktay OYMAK   +6 more
doaj   +1 more source

Bases genètiques de la febre mediterrània familiar a la població espanyola, dinàmica genòmica i història natural de les mutacions al locus "MEFV" [PDF]

, 2004
[cat] La febre mediterrània familiar (FMF) afecta unes 10.000 i 100.000 persones d'origen principalment àrab, armeni, turc i jueu i és caracteritza per la recurrència d'episodis autolimitats de febre i inflamació de seroses, sense una causa infecciosa ...
Aldea Tomé, Ana Isabel, Aldea Tomé, Anna   +1 more
core  

Comparison of Different Pharmaceutical Preparations of Colchicine in Children with Familial Mediterranean Fever: Is Colchicine Opocalcium a Good Alternative?

, 2021
Background: Colchicine is an anti-inflammatory agent used for preventing familial Mediterranean fever (FMF) attacks and amyloidosis.
Selçuk Yüksel, Unsal, Erbil, Serkan Türkuçar, Makay, BALAHAN, Acari, Ceyhun, Balahan Makay, Yukser, Selcuk, Yuksel, Selcuk, Ceyhun Acari, Gülçin Otar Yener, Erbil Ünsal, Turkucar, Serkan, Yener, Gulcin Otar, Hatice Adıgüzel Dundar, Dundar, Hatice Adiguzel   +14 more
core   +1 more source

PECU: A multicenter study on pediatric patients with cold‐induced urticaria

Pediatric Allergy and Immunology, Volume 37, Issue 6, June 2026.
Abstract Background Cold‐induced urticaria (ColdU) is a rare chronic inducible urticaria that can cause systemic reactions, including cold‐induced anaphylaxis (ColdA), but pediatric data are limited. The aim of this study was to evaluate the clinical characteristics, comorbidities, management approaches, risk of anaphylaxis, and long‐term course of ...
Betul Gemici Karaaslan, Ozgen Soyoz, Figen Celebi Celik, Humeyra Akbas, Yakup Canitez, H. Ilbilge Ertoy Karagol, Beril Canan Aksoydan, Yagmur Hazal Sadirvan Oguzkaya, Gizem Uslu, Semiha Bahceci Erdem, Ummugulsum Dikici, Hilal Gungor, Handan Duman Senol, Hulya Anil, Adem Yasar, Lida Bulbul, Nursen Cigerci Gunaydin, Ozge Turkyilmaz Ucar, Mehmet Akif Kaya, Sanem Eren Akarcan, Tugba Arikoglu, Ozge Kangalli Boyacioglu, Hatice Eke Gungor, Merve Ocalan, Mahmut Dogru, Mahir Serbes, Nagihan Iskender, Mehmet Kilic, Mutlu Yuksek, Ozlem Yilmaz, Tuba Tuncel, Sefika Ilknur Kokcu Karadag, Zeynep Meric, Tuba Karakurt, Sezin Aydemir, Ugurcan Sayili, Fadil Ozturk, Ozlem Sancakli, Aysen Bingol, Mehmet Halil Celiksoy, Mustafa Atilla Nursoy, Aylin Kont Ozhan, Suna Asilsoy, Ozge Yilmaz, Dilek Ozcan, Isil Eser Simsek, Koray Harmanci, Esen Demir, Deniz Ozceker, Oner Ozdemir, Sukru Cekıc, Mustafa Arga, Ozlem Cavkaytar, Nazli Ercan, Arzu Bakirtas, Zeynep Ulker Altinel, Demet Can, Haluk Cokugras, Esra Yucel, Ayca Kiykim   +59 more
wiley   +1 more source