Results 101 to 110 of about 88,550,665 (248)

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source

Dispositional Predictors of Work/Family Interface Among Working Women

SAGE Open
The current research was carried out to identify dispositional predictors of work/family conflict and enrichment faced by working women. Purposive sampling strategy was used to collect a sample of 265 working women, out of which 129 were married and 136 ...
Ayesha Sarfaraz, Ayesha Khalid, Zasheer Aman   +2 more
doaj   +1 more source

How does family support facilitate job satisfaction? Investigating the chain mediating effects of work–family enrichment and job‐related well‐being

, 2019
While a direct relationship between family support and job satisfaction has received empirical support, few work–family studies have examined how family support leads to job satisfaction. Drawing on the work–home resources model, we investigate the chain
Chan, Christopher, Kalliath, Thomas, Parveen Kalliath, Christopher Chan, Chan, Xi Wen, Thomas Kalliath, Kalliath, Parveen, Xi Wen Chan   +7 more
core   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

FEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas, Aaron D. Morgan, Ignas Čiurlionis, Christian Böhm, Stefan Jockenhövel, Willi Jahnen‐Dechent, Marc A. M. J. van Zandvoort   +6 more
wiley   +1 more source

The Impact of Work-Famıly Enrıchment on Work Engagement: Examınıng the Medıatıng Roles of Job Satısfactıon and Self-Effıcacy

APMBA (Asia Pacific Management and Business Application)
This research examines the effect of work-family enrichment on work engagement through self-efficacy and job satisfaction as mediating variables among women entrepreneurs in Bali.
Ni Made Dwi Puspitawati, Leni Marlina Kanadjo, Ni Nyoman Suliati, Ni Made Yudhaningsih   +3 more
doaj   +1 more source

Texas Work & Family Clearinghouse News

, 1998
Quarterly newsletter of the Texas Work & Family Clearinghouse discussing news, events, and other updates related to the work of the program, as well as other topics relevant to working parents and ...
Texas Work & Family Clearinghouse
core  

Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription

FEBS Open Bio, EarlyView.
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang, Mingqiang Deng, Dongmei He, Diqin Lai, Dongjun Liu, Dengyong Zhu, Zhenhua Zhang, Peng Tang, Chuanman Zhou, Menghui Yin, Xichen Bao   +10 more
wiley   +1 more source

How age-inclusive human resource practices relate to career sustainability: the role of work-family enrichment and protean career orientation

Frontiers in Psychology
Drawing on conservation of resource theory and work-home resources model, this study explores how age-inclusive human resource (HR) practices related to employees’ career sustainability through their work-family enrichment.
Liang Hou, Ruijing Shi, Zhongji Wang, Jun Zhang   +3 more
doaj   +1 more source