Results 41 to 50 of about 1,227,700 (219)

OVERCOMING THE DISCONNECTION BETWEEN SOCIO-PEDAGOGICAL PRACTICE AND LAW

Образование и наука, 2015
The aim of the study is to discuss an urgent problem of legislative consolidation of wide spectrum for socio-pedagogical services; to demonstrate to reveal the importance of the problem decision and significance of professional work of social teachers ...
Marina P. Guriyanova, Lyubov V. Shtilyeva, Olga L. Lebed, Roza A. Andrianova, Tatiyana P. Seppyanen   +4 more
doaj   +1 more source

Waist Circumference Is More Closely Associated with Hypogonadism than Is Hyperglycemia, Independent of BMI in Middle-Aged Men

Journal of Diabetes Research, 2021
Introduction. To evaluate whether waist circumference (WC) or hyperglycemia is more closely associated with hypogonadism in middle-aged men. Research Design and Methods. This cross-sectional study analyzed male participants under 65 years old from the MJ
Po-Sheng Hsu, Chia-Lien Hung, Shih-Kai Tu, Hsin-Hung Chen, Deng-Ho Yang, Chun-Cheng Liao   +5 more
doaj   +1 more source

The Effect Of Pregnancy Follow-Up On Birth Expectations In Primary Health Care

Ankara Medical Journal, 2021
INTRODUCTION: Pregnancy is a period with physical, emotional and social consequences. These results can be positive, such as joy and happiness, or negative, such as stress and anxiety. Negative consequences can cause fear of childbirth.
Bahadır Yazıcıoğlu, Muhammet Ali Oruç, Eda Türe, Seçil Müderrisoğlu, Mahcube Çubukçu   +4 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Usages numériques domestiques et réussite scolaire. Le rôle de la socialisation familiale

Recherches en Éducation
Digital technologies are playing an increasingly important role in schools – a situation that has been further accentuated by the COVID-19 pandemic – with the aim of renewing the school institution and reducing social inequalities in academic achievement.
Agnès Grimault-Leprince, Lila Le Trividic Harrache, Laurent Mell   +2 more
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

#225 : miR-135b Expression Correlated with Aneuploidy in Trophectoderm from IVF Patients: An Approach to NIR-Invasive Screening for Embryo Quality Assessment

Fertility & Reproduction, 2023
Background and Aims: MicroRNAs (miRNAs) are abundantly expressed in rapidly growing and undifferentiated cells, for example, embryonic stem cells. This led to the discovery that miRNAs are significantly expressed in human embryos and that intracellular ...
Kresna Mutia, Anom Bowolaksono, Ririn Rahmala Febri, Pritta Ameilia Iffanolida, Gita Pratama, Achmad Kemal Harzif, Mila Maidarti, Kanadi Sumapraja, R. Muharam, Andon Hestiantoro, Budi Wiweko   +10 more
doaj   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source