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Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani +6 more
wiley +1 more source

ANALYSIS OF THE CAUSES OF COMPANY PERFORMANCE IN FAMILY COMPANIES IN THE MANUFACTURING INDUSTRY

International Journal of Application on Economics and Business, 2023
The purpose of this study was to obtain empirical evidence on the effect of family ownership, firm size, firm age, family involvement on the board of commissioners, and family involvement on the board of directors on firm performance. In this study, secondary data was used tested using SPSS version 21.
Elisa Elisa, Hadi Cahyadi
openaire +1 more source

Artificial Intelligence and Mental Well‐Being in Adult Education: Implications for Practice and Professional Responsibility

New Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Mental well‐being is central to adult learner success, yet many adult education institutions lack capacity to provide timely and accessible support. This article examines how artificial intelligence (AI) can strengthen mental health–adjacent supports in adult and continuing higher education, with attention to professional practice and ...
Adam L. McClain, Thomas Wade
wiley +1 more source

Financial restatement and firm performance in family controlled and CEO duality companies: evidence from post 2007 Malaysian Code of Corporate Governance

SHS Web of Conferences, 2017
Do financial restatements dampen firm performance? One argument about this is that restatements hurt investor confidence in the credibility of a firm’s disclosure, resulting in a decline in demand for the firm’s securities, thereby, leading to a ...
Chin Sok Fun, Tang Kin Boon, Che Ahmad Ayoib +2 more
doaj +1 more source

Family Businesses in the Corporate Governance of MNCs

Acta Universitatis Agriculturae et Silviculturae Mendelianae Brunensis, 2015
The issue of family businesses is currently a very topical theme in the academic world. The importance of family businesses increases with internationalization and is associated with business success in global market conditions.
Pavla Odehnalová, Petr Pirožek
doaj +1 more source

Remote Assessment of Ataxia Severity in SCA3 Across Multiple Centers and Time Points

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Spinocerebellar ataxia type 3 (SCA3) is a genetically defined ataxia. The Scale for Assessment and Rating of Ataxia (SARA) is a clinician‐reported outcome that measures ataxia severity at a single time point. In its standard application, SARA fails to capture short‐term fluctuations, limiting its sensitivity in trials.
Marcus Grobe‐Einsler +20 more
wiley +1 more source

Influence of ownership structure and family management on the debt financing cost of brazilian publicly traded companies

RACE: Revista de Administração, Contabilidade e Economia, 2020
The objective of this study was to verify the influence of the structure of ownership and family management in the cost of debt financing of publicly traded companies listed in B3.
Geovanne Dias de Moura +4 more
doaj +1 more source

Family Company Direction Case [PDF]

, 2021
AbstractTwo brothers founded the sport retail shop “Outdoor Champions.” The company strived on their exquisite personal expertise and hands-on business skills. After reaching retirement age, they faced a company direction and succession challenge typical of family businesses. They resolved it in a simple, authentic and unconventional way.
openaire +1 more source

Clustering Algorithm Reveals Dopamine‐Motor Mismatch in Cognitively Preserved Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore the relationship between dopaminergic denervation and motor impairment in two de novo Parkinson's disease (PD) cohorts. Methods n = 249 PD patients from Parkinson's Progression Markers Initiative (PPMI) and n = 84 from an external clinical cohort.
Rachele Malito +14 more
wiley +1 more source

Catalan family companies with high growth during the crisis period

Intangible Capital, 2016
Purpose: This study aims to analyze the financial and economic health of the Catalan family companies with high growth during the crisis period (2008-2013), as an engine of job creation and economic development of the territory, identifying the economic ...
Nuria Arimany-Serrat, Elisenda Tarrats-Pons +1 more
doaj +1 more source

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