Results 91 to 100 of about 485,517 (308)
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Asian Nursing Researchsummary: Purpose: Stroke survivors and their informal family caregivers may share the impact of the disease, which may affect family functioning and quality of life (QoL) for both.
Chia-Chi Li +6 more
doaj +1 more source
Adolescent attachment, family functioning and depressive symptoms
South African Journal of Psychiatry, 2015 Background. Adolescence represents a challenging transitional period where changes in biological, emotional, cognitive and social domains can increase the risk of developing internalised problems including subthreshold depression.
Nishola Rawatlal +2 more
doaj +1 more source
a*‐families of analytic functions
International Journal of Mathematics and Mathematical Sciences, 1984 Using convolutions, a new family of analytic functions is introduced. This family, called a*‐family, serves in certain situations to unify the study of many previously well known classes of analytic functions like multivalent convex, starlike, close‐to‐convex or prestarlike functions, functions starlike with respect to symmetric points and other such ...
G. P. Kapoor, A. K. Mishra
openaire +3 more sources
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Family functioning, family social support, and life satisfaction among school adolescents in the Federal Land Development Authority (FELDA) area in Johor, Malaysia [PDF]
Adolescents' satisfaction with life can be influenced by various factors, including family environment factors. This study aimed to ascertain the relationship between family functioning and social support on adolescents’ life satisfaction in Johor ...
Azam, Naqi Dahamat +3 more
core +1 more source
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
, 2012 PhDDental caries is a public health problem affecting over 30% of 3.5 to 4.5 year old children in the UK. One of its most important determinants is frequent consumption of sugary foods, without which plaque bacteria cannot produce sufficient acids to ...
Nanjappa, Sucharita
core
Family Functioning, Self-Concept, and Severity of Adolescent Externalizing Problems
, 2006 We investigated direct and shared effects of family functioning and self-concept on the severity of adolescent externalizing problems in a sample of 224 clinically referred adolescents.
Henderson, Craig +7 more
core +1 more source
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source