Results 121 to 130 of about 4,817,785 (305)

Frequency of Prediabetes, Raised BMI and Low Plasma HDL-Cholesterol in Offspring of Diabetes

open access: yesJournal of the Dow University of Health Sciences, 2014
Background: World wide approximately 470 millions people are getting affected by a prediabetic state. Risk of diabetes is doubled when there is a family history of diabetes (FHD) in parents.
Meraj Rahim   +4 more
doaj  

Longitudinal study of local authority child and family social workers (wave 1) Findings from a 5 year study of local authority child and family social workers in England. [PDF]

open access: yes, 2019
The longitudinal study investigates recruitment, retention and career progression in local authority child and family social work over 5 years. This is the first of 5 reports.
Coburn, S   +10 more
core   +3 more sources

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

The seven servants of Ham: Labourer’s letters from Wellington in the New Zealand Journal, 1840-1845 [PDF]

open access: yes, 2010
Several years ago David Fitzpatrick noted that ‘the materials of family history’ had assumed increasing importance in studies of immigration. ‘[O]ld photographs, diaries and letters’, combined with genealogical methods, allow historians to ‘reconstitute ...
Middleton, Sue
core   +1 more source

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

open access: yesMolecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li   +10 more
wiley   +1 more source

Building a family ontology to meet consistency criteria [PDF]

open access: yes, 2015
Semantic web is an extension of the current web in which the existing information on the web are organized and encoded more meaningfully using ontology language, thus enabling effective communication among machines and humans. Ontology is the backbone
Tan, Mee Ting
core  

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

On Family History

open access: yesArchives of Clinical and Medical Case Reports, 2023
openaire   +2 more sources

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Southwesterly Town Lot Histories of Fairfield, Pennsylvania

open access: yes, 2013
Each lot history give the original lot number, original owner, the current address, the owner of the lot in 1860, a description of the lot or dwelling in 1860, a recital of ownership with as much detail as is known, a comprehensive lot history, any known
Smith, Timothy H.
core  

Home - About - Disclaimer - Privacy