Results 51 to 60 of about 158,238 (309)

Elderly in the state of co-residence in a town in State Bahia, Brazil

open access: yesO Mundo da Saúde, 2015
This study aims to describe the socioeconomic characteristics of the elderly and the level of individual and collective satis- faction in the structural and emotional aspects of family cohabitation. This is a cross-sectional, descriptive and exploratory
Saulo Sacramento Meira   +4 more
doaj  

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

open access: yesFEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig   +7 more
wiley   +1 more source

Housing systems in the Global South

open access: yesPlaNext, 2021
This paper addresses the problem of accessing decent and affordable housing in the Global South, where the housing need is, in general, more problematic than in the Global North.
Alireza Vaziri Zadeh   +2 more
doaj  

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

open access: yesFEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava   +3 more
wiley   +1 more source

Housing, family and children: Some of the issues in the transitional period [PDF]

open access: yesUrbani Izziv, 1995
The author deals with the process of transition in the multy-family housing sector particularly with regard to the family and children. She contends that the transitional period had a great effect on the rented sector and thus also affected potential ...
Srna Mandič
doaj  

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

open access: yesFEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani   +6 more
wiley   +1 more source

Identification of functional murine mitochondrial formyl peptides and their effects on myeloid‐derived suppressor cell generation

open access: yesFEBS Open Bio, EarlyView.
We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa   +2 more
wiley   +1 more source

How Housing Stress Affect Health Care Costs: A Panel Data Study

open access: yesInquiry: The Journal of Health Care Organization, Provision, and Financing
As housing prices in China continue to escalate and the limitations of the “personal unlimited liability system” for housing loans become more evident, the financial stress on families has significantly increased.
Gai Liu PhD   +2 more
doaj   +1 more source

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