Results 131 to 140 of about 4,182,366 (344)
YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma
Molecular Oncology, EarlyView.The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy +9 more
wiley +1 more source
WHAT’S IN A NAME? DEPARTMENTS OF FAMILY MEDICINE AND … [PDF]
, 2019 Amanda Weidner +4 more
openalex +1 more source
Emerging role of ARHGAP29 in melanoma cell phenotype switching
Molecular Oncology, EarlyView.This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster +3 more
wiley +1 more source
Achieving competencies in family medicine through continuing professional development [PDF]
, 2016 Jamie Meuser +3 more
openalex +1 more source
Review of: "Definition of Post-COVID-19 General practice / family medicine" [PDF]
, 2022 Sudip Bhattacharya
openalex +1 more source
The experience of Armenian family medicine residents with participatory learning methods in rural health centres [PDF]
, 2018 Introduction: The Family Medicine residency program in Armenia relies on traditional teacher- centred and didactic learning methods. The program is largely classroom based. Learning through contact with patients is limited.
Antonyan, Lusine +3 more
core
Molecular Oncology, EarlyView.In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern +7 more
wiley +1 more source
Family medicine predoctoral education: 30-something [PDF]
, 2007 From the introduction: The specialty of family medicine is now more than 30 years old. Fitting for its stage of life, family medicine predoctoral education has achieved appropriate maturity and parity with other core clinical departments and has assumed ...
Rabinowitz, Howard K.
core
Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine
Molecular Oncology, EarlyView.The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu +18 more
wiley +1 more source