Results 31 to 40 of about 223,432 (325)

The relationship between famine exposure during early life and body mass index in adulthood: A systematic review and meta-analysis.

open access: yesPLoS ONE, 2018
BackgroundPrevious epidemiologic studies have reported famine exposure during early life association with overweight or obesity in adulthood, but a consistent perspective has not been established to date.PurposeTo determine, by conducting a systematic ...
Jielin Zhou   +9 more
doaj   +1 more source

Differential effect of prenatal exposure to the Great Ethiopian Famine (1983–85) on the risk of adulthood hypertension based on sex: a historical cohort study

open access: yesBMC Women's Health, 2022
Background The consequence of the Great Ethiopian Famine (1983–1985) on mortality had been well documented. However, the long term assaults of the famine on adulthood health, particularly on the risk of hypertension, has never been documented. The aim of
Kalkidan Hassen Abate   +4 more
doaj   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

open access: yesMolecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad   +12 more
wiley   +1 more source

Association between exposure to the Chinese Famine in different stages of early life and decline in cognitive functioning in adulthood

open access: yesFrontiers in Behavioral Neuroscience, 2016
Objective: To investigate whether exposure to the Chinese Famine in different life stages of early life is associated with cognitive functioning decline in adulthood.Methods: We recruited 1366 adults born between 1952 and 1964 and divided them into fetal-
Chao Wang   +7 more
doaj   +1 more source

CEOs’ early famine experience, managerial discretion and corporate social responsibility

open access: yesHumanities & Social Sciences Communications, 2023
Corporate social responsibility (CSR) reflects entrepreneurs’ early life experiences in reality. Based on imprinting theory and upper echelons theory, this paper examines the impact of a CEO’s early famine experience on CSR, analyzes the moderating ...
Zhaocheng Xu
doaj   +1 more source

The trigger of Ethiopian famine and its impacts from 1950 to 1991

open access: yesCogent Arts & Humanities, 2023
Ethiopia is an ancient state that emerged in the Horn of Africa. The country has an abundance of natural resources, a rich history, cultures, languages, and diverse physical landscapes.
Dagm Alemayehu Tegegn
doaj   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

How Chief Executive Officers’ first-hand experience of the Great Chinese Famine affects risk-taking?

open access: yesHumanities & Social Sciences Communications, 2023
To understand the influence of Chief Executive Officers’ (CEOs) early life experiences on their firms’ strategic decision-making, here we explore the impacts of CEOs’ experience of the Great Chinese Famine (1959–1961) on their cognitions and firm risk ...
Dayuan Li, Chen Huang, Ding Wang
doaj   +1 more source

Daratumumab Treatment for Chronic Inflammatory Demyelinating Polyradiculoneuropathy (CIDP): A Case Report

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) is an immune‐mediated neuropathy featuring progressive weakness, sensory deficits, and areflexia. While corticosteroids, intravenous immunoglobulin, and plasmapheresis are effective first‐line immunotherapies, a subset of patients remains treatment‐refractory.
Xueyu Zhang   +8 more
wiley   +1 more source

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