Results 101 to 110 of about 70,491 (173)

Loss of Fanconi anemia proteins causes a reliance on lysosomal exocytosis. [PDF]

Cell Death Dis
Fu BXH, Xu A, Li H, Johnson DE, Grandis JR, Gilbert LA.   +5 more
europepmc   +1 more source

Fanconi Anemia

Fanconi anemia (FA) is characterized by bone marrow failure, malformations, and chromosome fragility. We review the recent discovery of FA genes and efforts to develop genetic therapies for FA in the last five years. Because current data exclude FANCM as an FA gene, 15 genes remain bona fide FA genes and three (FANCO, FANCR and FANCS) cause an FA like ...
Bhandari J, Thada PK, Killeen RB, Puckett Y.   +3 more
europepmc   +2 more sources

Dynamics of Fanconi anemia protein D2 in association with nuclear lipid droplet formation. [PDF]

J Cell Sci
Hotani T, Goto M, Otsuki Y, Matsuda S, Wada N, Shinohara M, Matsuda T, Yokoi M, Sugasawa K, Ohsaki Y, Sakai W.   +10 more
europepmc   +1 more source

Another Fanconi anemia gene joins the club. [PDF]

J Clin Invest
Homan CC, Scott HS, Venugopal P.
europepmc   +1 more source

PRMT5 inhibition impairs Fanconi Anemia pathway-mediated homologous recombination and enhances the antitumor efficacy of Temozolomide in glioblastoma. [PDF]

Cell Death Dis
Onishi S, Jayamohan S, Chowdhury A, Rivas S, Otani Y, Ertekin C, Bryant JP, Murphy SA, Rivera-Caraballo KA, Walbridge S, Sisay B, Maric D, Elkahloun A, Johnson K, Brown DA, Heiss JD, Shah AH, Lee TJ, Kumbar SG, Yoo JY, Brenner AJ, Kaur B, Sareddy GR, Banasavadi-Siddegowda YK.   +23 more
europepmc   +1 more source

Clinical and genetic spectrum of Fanconi anemia in Australia and New Zealand. [PDF]

Genet Med Open
Fluhler H, Granger E, Sharp M, Harris C, McKinley M, Riyat S, Krieg C, Deans A, Fraser C, Cross S, Carter T, Worgan L, Nelson A, Fox LC, Nicholl J, Attwood A, McLeman L, Hughes D, Conyers R, Kujan O, Velleuer-Carlberg E, Nandini A, Crismani W.   +22 more
europepmc   +1 more source

Deficiencies in the Fanconi anemia or homologous recombination pathway enhance the antitumor effects of the hypoxia-activated prodrug CP-506. [PDF]

Mol Ther Oncol
Schuitmaker L, van der Wiel AMA, Lieuwes NG, Biemans R, Mutsters NAM, Jung J, Bastos VC, Sagarra ÈP, Kuang S, Setton J, Langie SAS, Kampen KR, Theys J, Yaromina A, Dubois LJ, Lambin P.   +15 more
europepmc   +1 more source

Patient-derived xenograft models of Fanconi anemia-associated head and neck cancer identify personalized therapeutic strategies. [PDF]

J Clin Invest
Grandis JR, Li H, Harrison BA, Webster AL, Pucilowska J, Nguyen A, Lee J, Mills GB, Gencel-Augusto J, Zeng Y, Long SR, Kim MO, Lee RH, Kutler DI, Scognamiglio T, Brandwein-Weber M, Urken M, Khodos I, de Stanchina E, Lin YC, Donovan FX, Chandrasekharappa SC, Jung M, Sanders MA, Smogorzewska A, Johnson DE.   +25 more
europepmc   +1 more source

Fanconi Anemia

National Journal of Health Sciences, 2019
Saima Siddiqui, Tahir Sultan Shamsi
openaire   +1 more source

Heterozygous Germline Fanconi Anemia-Related Gene Mutations Increase Susceptibility to Germ Cell Tumors. [PDF]

JCO Precis Oncol
Wang J, Luo N, Han T, Yin X, Wang G.
europepmc   +1 more source