Results 91 to 100 of about 4,179 (208)

Preclinical evaluation of DOTAGA.Glu.(FAPI)2 and DO3A.Glu.(FAPI)2 as theranostics with human dosimetry extrapolation to lutetium-177 and terbium-161 analogs.

Purpose This study aims to assess DOTAGA.Glu.(FAPI)2 and DO3A.Glu.(FAPI)2, specifically engineered as precursors for the development of theranostic FAPI-targeted radioligands.Methods DOTAGA.Glu.(FAPI)2 and DO3A.Glu.(FAPI)2 were radiolabeled with gallium ...
Naveen, Kumar, Läppchen, Tilman, Martin, Marcel, Gnesin, Silvano, Menéndez, Elena, Gourni, Eleni, Rominger, Axel, Bilinska, Adrianna, Rösch, Frank   +8 more
core   +2 more sources

FAPI-negative Papillary Renal Cell Carcinoma With Markedly FAPI-avid Sacral Insufficiency Fracture

We report a 77-year-old woman with papillary renal cell carcinoma showing no increased [ 68 Ga]Ga-FAPI uptake in the primary tumor, while intense sacral FAPI uptake mimicked bone metastasis ...
Enes Yerdes, Ertan Sahin
core   +1 more source

Recent implications of FAPI PET in cardiac diseases

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Fibroblast activation protein (FAP), highly expressed in activated fibroblasts within injured myocardium, serves as the molecular target for FAP inhibitor (FAPI)‐based imaging.
Lan Wang, Shixing Huang, Fengling Shan, Jingjing Lou, Xingdang Liu   +4 more
doaj   +1 more source

Impact of 68Ga-FAPI positron emission tomography/computed tomography on staging and tumor management in patients with gastric cancer

Journal of Cancer Research and Clinical Oncology
Purpose To evaluate the added value of additional 68Ga-FAPI PET/CT following CT for primary staging, detection of postoperative recurrence, and management of gastric cancer patients.
Shunyu Zhang, Minggang Su, Qianrui Li, Qiancheng Hu, Xijiao Liu, Xiaolong Chen, Hongfeng Gou   +6 more
doaj   +1 more source

Imaging with 68Ga-FAPI PET/CT: Results from a FAPI Registry Study

World Journal of Nuclear Medicine, 2022
Nader Hirmas, Miriam Sraieb, Lukas Kessler, Kim M. Pabst, Timo Bartel, Rainer Hamacher, Jens T. Siveke, Stefan Kasper, Ken Herrmann, Wolfgang P. Fendler   +9 more
openaire   +1 more source

Enhanced Pancreatitis Detection: FAPI PET/CT Emerging Utility in Patient with Pancreatic Mass

Diagnostics
Fibroblast Activation Protein Inhibitor (FAPI) positron emission tomography (PET) imaging has emerged as a useful method for identifying pancreatic disorders, notably pancreatitis.
Alain Abi Ghanem, Tamara El Annan, Nour El Ghawi, Nadine Omran, Mustafa Natout, Hazem Assi, Ali Shamseddine, Nina Saliba, Mohamad Haidar   +8 more
doaj   +1 more source

Therapeutic potential of FAPI RLT in oncology: A systematic review

Rationale: This systematic review aims to examine the safety and efficacy of fibroblast activation protein inhibitor (FAPI) radioligand therapy (RLT) for various epithelial neoplasms. Methods: PubMed, Web of Science, and Scopus databases were searched up
Moghrabi, S, Ruzzeh, S, Paez, D, Kang, KW, Watabe, T, Al-Ibraheem, A, Abdlkadir, AS, Scott, AM   +7 more
core   +1 more source

Is There a Role for FAPI PET in Urological Cancers?

this work aims to investigate the utility of positron emission tomography/computed tomography (PET/CT) with fibroblast activation protein inhibitors (FAPI) in urological neoplasms, including prostate cancer, urothelial carcinoma, and renal cell carcinoma.
Zamberlan I., Ortolan N., Filippi L., Bartolomei M., Urso L., Uccelli L., Cittanti C., Buffi N. M., Evangelista L.   +8 more
core   +2 more sources

Head-to-head comparison of the detection performance and tumor uptake of 68Ga-FAPI-04 and 18F-FDG PET/CT in liver metastases from malignant tumors of different types

Holistic Integrative Oncology
Objective We sought to compare the detection performance and tumor uptake of 68Ga-FAPI-04 and 18F-FDG in liver metastases from malignant tumors of different types. Methods A total of 76 patients were included between May 2020 and April 2023.
Guang Ma, Cheng Liu, Ming Qi, Jindian Li, Shaoli Song   +4 more
doaj   +1 more source

Fibroblast Activation Protein Inhibitor (FAPI)-Based Theranostics

Fibroblast activation protein (FAP) is a serine protease selectively expressed in cancer-associated fibroblasts (CAFs), fibrotic tissues, and areas of active tissue remodeling, making it an attractive target for diagnostic imaging across a spectrum of ...
Bawinile Hadebe, William Serumula, Venesen Pillay, Mariza Vorster   +3 more
core   +1 more source