Results 71 to 80 of about 4,179 (208)

Design and imaging performance of BPET–DBT – a dedicated scanner for breast imaging

Medical Physics, Volume 53, Issue 9, September 2026.
Abstract Background A dedicated breast PET (BPET) scanner integrated with digital breast tomosynthesis (DBT) enables three‐dimensional functional imaging with quantitative information co‐registered to high‐resolution anatomical images. With the availability of breast cancer specific PET radiotracers, such a scanner has the potential to improve ...
Srilalan Krishnamoorthy, Emmanuel Morales, William J. Ashmanskas, Matthew E. Werner, Samuel Matej, Juhi Raj, Trevor L. Vent, Chloe J. Choi, Andrew D. A. Maidment, David A. Mankoff, Christine E Edmonds, Joel S Karp, Suleman Surti   +12 more
wiley   +1 more source

Preclinical Evaluation and a Pilot Clinical Positron Emission Tomography Imaging Study of [⁶⁸Ga]Ga-FAPI-FUSCC-II

Fibroblast activation protein (FAP), a type II integral membrane serine protease, is a promising target for tumor diagnosis and therapy. OncoFAP has been recently discovered for PET imaging procedures for various solid malignancies.
Bingxin Gu (6715919), Xiao Wang (19312), Zhongyi Yang (206009), Shaoli Song (412493), Xiangwei Wang (145471), Xinyue Du (5958476), Mengjing Ji (17741338), Jianping Zhang (161794), Simin He (3844873), Xiaoping Xu (325842)   +9 more
core   +1 more source

Development of a Synthetic Method for [68Ga]Ga-FAPI-04 Using a Cassette-based Synthesizer

Korean Journal of Clinical Laboratory Science
[68Ga]Ga-FAPI-04 is a promising radiopharmaceutical that binds specifically to fibroblast activation protein, which is overexpressed in more than 90% of malignant epithelial tumors but not in normal healthy tissue.
Jun Young PARK, Won Jun KANG
doaj   +1 more source

PSYNDEX Tests Review für FAPI - Flugangst- und Flugphobie-Inventar

, 2012
This is a PSYNDEX Tests Review of FAPI - Flugangst- und Flugphobie-Inventar. PSYNDEX Tests Reviews are written in German and describe and evaluate psychological and educational tests used in the German-speaking countries.
Mayer, Anne-Kathrin
core   +1 more source

Imaging the Tumor Microenvironment Beyond Anatomy: Functional, Immune, Stromal, and Metabolic Signatures for Precision Oncology

iRADIOLOGY, Volume 4, Issue 4, Page 287-304, August 2026.
This article highlights the importance of imaging the tumor microenvironment (TME) beyond conventional anatomy‐based approaches to enable more precise oncology. It focuses on capturing key biological dimensions of tumors—vascular function and hypoxia, immune response, stromal remodeling, and metabolic activity—using advanced imaging techniques.
Karthikeyan Elumalai, Gayathri Krishnakumar   +1 more
wiley   +1 more source

PET Imaging of Cardiac Inflammation in Viral Myocarditis Using a DPP4‐Targeted Probe

Advanced Science, Volume 13, Issue 38, 9 July 2026.
This study describes a DPP4‐targeted PET probe for imaging myocardial inflammation by selectively targeting activated immune cells. Derived from the clinically approved small‐molecule inhibitor linagliptin, the probe demonstrates favorable biodistribution with specific cardiac uptake in myocarditis.
Wanhao Gao, Wenzhu Hu, Du Tang, Xinxin Liu, Kun Yu, Lixia Feng, Minyu Liao, Wang Lin, Wenqiang Zhu, Sanjay Rajagopalan, Xiaoli Lan, Jixin Zhong, Dao Wen Wang, Dawei Jiang, Xiaoquan Rao   +14 more
wiley   +1 more source

Preclinical and Clinical PET Imaging Studies of FAP and αⅤβ3 Dual Targeting Molecular Probes [18F]AlF-NOTA-FAPI-RGD

Yuanzineng kexue jishu
This study aims to investigate the heterodimeric probe [18F]AlF-labeled targeting both fibroblast activation protein (FAP) and integrin receptor αⅤβ3: 1,4,7-triazacyclononane-1,4,7-triacetic acid-FAP inhibitor-arginine-glycine-aspartic acid (NOTA-FAPI ...
WU Xiaoming1, 2, WEN Xuejun2, 3, XUE Yun1, 4, TIAN Guoxin4, LIN Min2, TANG Mingze2, MA Fuqiu1, 4
doaj   +1 more source

68Ga-FAPI PET in detection of 18F-FDG PET Negative Cholangiocarcinoma: A Case Report on Alternative Molecular Imaging in Biliary Tract Malignancy

Journal of the Pakistan Medical Association
Fibroblast activation protein inhibitors (FAPI) PET is a new imaging approach that targets the cell population in the tumour surrounding stroma, particularly cancer-associated fibroblasts, rather than tumour cells.
Sharjeel Usmani, Anjali Jain, Khulood al Riyami, Asiya al Busaidi, Asim Jamal Shaikh   +4 more
doaj   +1 more source

Characteristics of 18F-FAPI-04 PET/CT in patients with peritoneal metastasis and to predict treatment efficacy, a head-to-head comparison with 18F-FDG PET/CT

Cancer Imaging
Background 18F-FAPI-04 PET/CT shows promise in detecting peritoneal metastases (PM), but its superiority over 18F-FDG PET/CT for lesion detection and predicting chemotherapy benefit remains unclear.
Yafei Zhang, Mimi Xu, Yu Wang, Fang Yu, Xinxin Chen, Guangfa Wang, Kui Zhao, Hong Yang, Xinhui Su   +8 more
doaj   +1 more source

Synthesis and Preliminary Evaluation of FAPα Targeted Tracer 131I-FAPI-03

Journal of Isotopes
: Using N-(4-quinolinoyl)-Gly-(2-cyanopyrrolidine) as scaffold, we prolonged the linker with serine to obtain a FAPI derivative ATE-FAPI-03, which was subsequently labeled with 131I by electrophilic substitution. Then the in vitro stability, Log P value,
MA Huan1, 2, LIAO Jiali2, YANG Yuanyou2, LIU Ning2, LI Feize2
doaj   +1 more source